Dynamics of immunoinflammatory markers level on the background of quercetin therapy in patients with ischemic heart disease associated with hypothyroidism

Abstract

ДИНАМІКА РІВНІВ ІМУНОЗАПАЛЬНИХ МАРКЕРІВ НА ТЛІ ТЕРАПІЇ КВЕРЦЕТИНОМ У ХВОРИХ НА ІШЕМІЧНУ ХВОРОБУ СЕРЦЯ, АСОЦІЙОВАНУ З ГІПОТИРЕОЗОМ© Results. Under the influence of basic therapy including quercetin there was noticed the reliable decrease of endotelin-1 and alpha-tumor necrosis factor, was detected the tendentious decrease of tissue activator inhibitor plasminogen-1, C-reactive protein and neopterin in 3 month of treatment. Conclusions. Basic therapy with quercetin as an additional preparation has a normalizing influence on the systemic inflammatory process and endothelial dysfunction and that grounds the expediency of the use of this complex pharmacotherapy in patients with ischemic heart disease associated with hypothyroidism