Dynamics of the ion cyclotron resonance effect on amino acids adsorbed at the interfaces

Abstract

In this study we show a reproduction of the Zhadin experiment, which consists of the transient increase of the electrolytic current flow across an aqueous solution of L-arginine and L-glutamic acid induced by a proper low frequency alternating magnetic field superimposed to a static magnetic field of higher strength. We have identified the mechanisms that were at the origin of the so-far poor reproducibility of the above effect: the state of polarization of the electrode turned out to be a key parameter. The electrochemical investigation of the system shows that the observed phenomenon involves the transitory activation of the anode due to ion cyclotron frequency effect, followed again by anode passivation due to the adsorption of amino acid and its oxidation products. The likely occurrence of similar ion cyclotron resonance (ICR) phenomena at biological membranes, the implications on ion circulation in living matter, and the consequent biological impact of environmental magnetic fields are eventually discussed.

Effect of weak static and low‐frequency alternating magnetic fields on the fission and regeneration of the planarian dugesia (Girardia) tigrina

“…These authors showed that combined magnetic fields produce a marked effect on biological objects if they are adjusted to the ion cyclotron frequency of Ca 2þ . We have shown that the same approach to the calculation of effective frequencies is applicable to the ionic forms of some amino acids [Novikov and Zhadin, 1994], which was confirmed by later studies [Zhadin et al, 1998;Pazur, 2004;Comisso et al, 2006]. Indeed, at physiological pH values, the ionic form of the arginine molecule has an excessive positive charge (isoelectric point of arginine 11.15), which can be taken into account in the calculation by the formula of ion cyclotron resonance.…”

Effects of Static and Low-Frequency Alternating Magnetic Fields on the Ionic Electrolytic Currents of Glutamic Acid Aqueous Solutions

“…Peaks in the ionic electrolytic current of aqueous amino acid solutions placed in a static magnetic field of flux density between 10 and 80 mT, with a superimposed alternating magnetic field with frequency between 1 and 10 Hz and a flux density between 20-80 nT have been observed by some researchers (Zhadin et al, 1998;Del Giudice et al, 2002;Pazur, 2004;Comisso et al, 2006), arousing considerable interest in the biomedical studies. However, other researchers have repeated the experiment and have not observed the appearance of peaks (Adair, 2000).…”

“…The experimental set up is similar to the one used by other researchers (Zhadin et al, 1998;Pazur, 2004;Comisso et al, 2006). Particular care has been devoted to the accuracy and control of all the experimental parameters, entering the measurements, both physical and chemical.…”

Deprotonation of glutamic acid induced by weak magnetic field: An FTIR‐ATR study

“…Experiments such as this followed the discovery in 1985 of an unusual resonance effect caused by a simultaneous weak DC and low frequency AC magnetic field in concentrations of calcium in the nervous tissue [Liboff, 1985]. Although controversial, the unexpected Zhadin effect has been observed by a number of independent researchers [Pazur, 2004;Comisso et al, 2006;Giuliani et al, 2008], and the origin of the current has been explained as a consequence of the dynamics of the ions in the arrangement of the coherent domains of water [Del Giudice et al, 2002].…”