Dynamics of Uptake of Estrogens and Androgens by Human Endometrium

Gurpide, Erlio; Welch, Margaret T.

doi:10.1016/s0021-9258(18)63641-5

Cited by 69 publications

(2 citation statements)

References 22 publications

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“…Twombley et al (1961) in a study after injection of 14C-labelled estradiol, showed less excretion in obese than lean subjects and speculated that estrogen could be stored in fat and gradually escape giving chronic stimulation. Double isotope dilution studies stimulated by the technique of Gurpide in our group give promise of further elucidation of these problems, though metabolic tissue studies may be still more significant (Gurpide & Welch 1969).…”

Section: Epidemiologymentioning

confidence: 99%

A Strategy for the Control of Endometrial Cancer

Gusberg

1975

Proceedings of the Royal Society of Medicine

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Section: Epidemiologymentioning

confidence: 99%

A Strategy for the Control of Endometrial Cancer

Gusberg

1975

Proceedings of the Royal Society of Medicine

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“…Τα οιστρογόνα εισέρχονται μέσα στο κύτταρο με παθητική διήθηση (91). Ο ρυθμός της εισόδου των στερινοειδών ορμονών εξαρτάται εν μέρει από τη συγκέντρωση τους (37). Οι κυτταρικοί υποδοχείς δε συμ μετέχουν στο μηχανισμό εισόδου των στερινοειδών ορμονών και οι οιστρογονικές ορμόνες δε αναστέλλουν την είσοδο οιστρογονικών ουσιών όπως την διαιθυλστιλβεστρόλη (38).…”

Section: γ1 είσοδος των οιστρογόνων στο κύτταρο και δέσμευση τους με τους κυτταροπλασματικούς υποδοχείςunclassified

Υποδοχεις Οιστρογονων Και Προγεστερονης Των Νεοπλασματων Του Ενδομητριου

Μαυρακη-Νταβου¹

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Steroid hormone receptors in carcinoma of the cervix

Hunter¹,

Longcope²,

Keough³

1987

Cancer

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To correlate the presence of specific steroid receptors with certain characteristics of cervical carcinoma, cytosol estrogen receptors (ERc) were measured in 70 cases of cervical carcinoma, and progesterone receptors (PRc) were measured in 56 of these cases; ERc and PRc were also measured in 17 normal cervices. Measurements were made using a dextran-coated charcoal technique involving a seven-point Scatchard plot analysis. In carcinoma of the cervix significant numbers of ERc (>3 fmol/mg protein) were found in 41% of the cases, and of PRc (>3 fmol/mg protein) in 30%; only 28% of the 56 cases contained both ERc and PRc. In the normal cervices, 59% contained significant levels of ERc and 41% significant levels of PRc. No correlation was found between ERc and PRc and menopausal status of the patient, stage, cell type, or histologic grade of the tumor. A weak (P = 0.063) correlation between the presence of PRc and length of survival was also found, but there was no correlation between ERc and survival. Unlike the situation for breast cancer, measurement of ERc and PRc appears to add little of value to the clinical management of cervical carcinoma.

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Dynamics of Uptake of Estrogens and Androgens by Human Endometrium

Cited by 69 publications

References 22 publications

A Strategy for the Control of Endometrial Cancer

A Strategy for the Control of Endometrial Cancer

Υποδοχεις Οιστρογονων Και Προγεστερονης Των Νεοπλασματων Του Ενδομητριου

Steroid hormone receptors in carcinoma of the cervix

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