Dysfunctional HDL and Cardiovascular Disease Risk in Individuals with Diabetic Dyslipidemia

Elboudwarej, Omeed

doi:10.4172/2155-6156.s4-001

Cited by 8 publications

(6 citation statements)

References 122 publications

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“…Another function of HDL is to prevent endothelial dysfunction by decreasing the expression of adhesion molecules, increasing the production of nitric oxide (NO), lowering and preventing apoptosis of endothelial cells. 26,27 The HDL levels in this study were not found to correlate with hsCRP levels. In contrast to the above explanation, some studies have not always observed the function of HDL in preventing the formation of atherosclerosis.…”

Section: Discussioncontrasting

confidence: 75%

Correlation between lipid profile and C-reactive protein in children with nephrotic syndrome

Astuti¹,

Muryawan²,

Mellyana³

2015

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Background Nephrotic syndrome (NS) causes dyslipidemia in children, which can be long term or intermittent. Dyslipidemia has long been established as a risk factor for atherosclerosis. An early sign of atherosclerosis is elevated high sensitivity C-reactive protien (hsCRP). Atherosclerosis early in life, especially in childhood, warrants an assessment for NS. Study on a correlation between lipid profile and hsCRP, as a marker of atherosclerosis, in pediatric NS patients has been limited.Objective To assess for a correlation between lipid profile and hsCRP in childhood nephrotic syndrome.Methods This cross-sectional study was undertaken on 29 children with NS in Dr. Kariadi Hospital. Serum hsCRP, total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) were examined in the active phase. Spearman's test was used to analyze a possible correlation between total cholesterol, LDL, HDL and hsCRP levels.Results Mean levels of total cholesterol (454 mg/dL) and LDL (288 mg/dL) in this study were high, while the HDL level (55 mg/dL) was normal, according to US Department of Health and Human Services classifications. The median hsCRP level was 0.33 mg/L and 9 (31%) subjects had high hsCRP levels of more than 1 mg/L. There was a positive correlation between LDL level and hsCRP (r=0.423; P<0.05). ConclusionsThere is a weak positive correlation between LDL and hsCRP levels in children with NS. [Paediatr Indones. 2015;55:1-6.].

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Section: Discussioncontrasting

confidence: 75%

Correlation between lipid profile and C-reactive protein in children with nephrotic syndrome

Astuti¹,

Muryawan²,

Mellyana³

2015

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“…In spite of therapeutic lifestyle changes and current lipid lowering therapy, many diabetic patients do not reach target lipid levels to decrease their cardio vascular risk [85]. Therefore, the search for new hypo lipidemic drugs and supplements is of considerable interest.…”

Section: Resultsmentioning

confidence: 99%

Phytotherapy for diabetic dyslipidemia: evidence from clinical trials

Ghorbani¹

2013

Clinical Lipidology

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“…HDL-C value o f less than 40 mg/dL significantly increases the risk for both atherosclerosis and AMI (Elboudwarej, Hojjat, Safarpoor, Vazirian, & Ahmadi, 2011;Cutler et al, 2000;Shepherd, 2005).…”

Section: Myocardial Infarction-epidemiology and Risk Factorsmentioning

confidence: 99%

Association between acute myocardial infarction and periodontitis: A case-control study with north Indian population.

Sidhu¹

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Dysfunctional HDL and Cardiovascular Disease Risk in Individuals with Diabetic Dyslipidemia

Cited by 8 publications

References 122 publications

Correlation between lipid profile and C-reactive protein in children with nephrotic syndrome

Correlation between lipid profile and C-reactive protein in children with nephrotic syndrome

Phytotherapy for diabetic dyslipidemia: evidence from clinical trials

Association between acute myocardial infarction and periodontitis: A case-control study with north Indian population.

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