Dysfunctional lens syndrome: a prospective review

Haddad, Jorge Selem; Rocha, Karolinne Maia; Waring, George O.; Faria-Correia, Fernando; Júnior, Renato Ambrósio

doi:10.37039/1982.8551.20210037

Cited by 3 publications

(1 citation statement)

References 22 publications

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“…Due to its progressive or gradual nature, DLS is identified mainly through imaging methods and treated when early diagnosed. Recently, Haddad et al (9) described the first and second stages of DLS as being characterized by loss of accommodation. A mild cataract is observed in the third stage, accompanied by loss of transparency of the lens, leading to a loss of visual quality.…”

Section: Introductionmentioning

confidence: 99%

The role of the tear film in dysfunctional lens syndrome: a prospective review

Mota¹,

Haddad²,

Rocha³

et al. 2022

Revista Brasileira De Oftalmologia

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Dry eye disease comprises a spectrum of disorders that cause unstable tear film with an irregular surface. Preexisting dry eye disease poses challenges during cataract surgery in chronic inflammation since preoperative biometry measurements are highly dependent on a smooth and healthy tear film. Following the recent approval by the Conselho Federal de Medicina, lens replacement procedures have become legal in Brazil and are indicated for patients over 55 years of age who have presbyopia with moderate or high hyperopia. As a result, patients have higher expectations for accurate refractive outcomes and excellent quality of vision after intraocular lens implantation. This review aims to provide ophthalmologists with decisive criteria for approaching and treating patients with dry eye disease at various stages of dysfunctional lens syndrome. RESUMOA doença do olho seco compreende um espectro de distúrbios que causam instabilidade do filme lacrimal com superfície irregular. A doença do olho seco preexistente apresenta desafios durante a cirurgia de catarata na inflamação crônica, uma vez que as medições biométricas pré-operatórias são altamente dependentes de uma superfície lacrimal regular e saudável. Após a recente aprovação pelo Conselho Federal de Medicina, os procedimentos de substituição de lentes tornaram-se legais no Brasil e são indicados para pacientes com mais de 55 anos que apresentam presbiopia com hipermetropia moderada ou alta. Como resultado, os pacientes têm melhores expectativas de resultados refrativos precisos e excelente qualidade de visão após o implante de lentes intraoculares. Esta revisão de literatura visa fornecer aos oftalmologistas critérios decisivos para abordagem e tratamento de pacientes com doença do olho seco em vários estágios da síndrome disfuncional do cristalino.

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Section: Introductionmentioning

confidence: 99%

The role of the tear film in dysfunctional lens syndrome: a prospective review

Mota¹,

Haddad²,

Rocha³

et al. 2022

Revista Brasileira De Oftalmologia

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Dysfunctional lens syndrome: a literature review

Borisov,

Loskutov

2024

jour

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Introduction. The term “Dysfunctional Lens Syndrome” (DLS) refers to age-related changes in the lens, including early cataracts and presbyopia, that do not significantly reduce visual acuity. This syndrome is characterized by a decrease in accommodative amplitude, an increase in light scattering, and a reduction in contrast sensitivity. With rising life expectancy, the prevalence of DLS is increasing, necessitating a more in-depth study of the pathogenic mechanisms underlying the syndrome and the refinement of its diagnostic criteria to establish standards for treatment correction. Aim: to summarize information on the pathogenesis of DLS, the potential for staging the syndrome using objective examination methods, and to provide treatment recommendations. Materials and methods. A bibliographic study of scientific publications was conducted using the Pubmed, ScienceDirect, and Cyberleninka databases. Literature sources were searched using the following keywords: dysfunctional lens syndrome (DLS), presbyopia correction, cataract, age-related lens changes. A total of 32 publications, primarily from the last 10 years, were included in the study from more than 100 viewed sources. Results. The DLS encompasses a wide range of conditions, from early stages characterized by a loss of accommodative amplitude and minor refractive anomalies to later stages involving a decrease in visual acuity and quality due to increased light scattering and aberrations. Currently, the evaluation of age-related lens changes involves assessing visual acuity and determining the degree of lens opacification using slit-lamp examination. Additionally, objective instrumental methods, such as optical coherence tomography and Scheimpflug imaging, can be used to assess the degree of lens opacification. Various methods are employed for the correction and treatment of DLS, ranging from glasses and contact lenses to surgical interventions, such as lens extraction and intraocular lens implantation. Research is also ongoing into drugs aimed at slowing the progression of lens changes. Conclusion. The term “Dysfunctional Lens Syndrome” is currently used to describe early cataracts and presbyopia, where the reduction in visual acuity is still minor, but patients experience visual complaints due to age-related lens changes. Further research is necessary to develop and standardize diagnostic criteria and to evaluate the effectiveness of new treatment methods and interventions in order to create the most effective and adequate approach to correcting DLS and alleviating the associated visual complaints.

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