In modern decentralised health systems, district and local managers are increasingly responsible for financing, managing, and delivering healthcare. However, their lack of adequate skills and competencies are a critical barrier to improved performance of health systems. Given the financial and human resource, constraints of relying on traditional face-to-face training to upskill a large and dispersed number of health managers, governments, and donors must look to exploit advances in the education sector. In recent years, education providers around the world have been experimenting with blended learning; that is, amalgamating traditional face-to-face education with web-based learning to reduce costs and enrol larger numbers of students. Access to improved information and communication technology (ICT) has been the major catalyst for such pedagogical innovations. We argue that with many developing countries already improving their ICT systems, the question is not whether but how to employ technology to facilitate the continuous professional development of district and local health managers in decentralised settings. Keywords: Blended Learning, Decentralisation, Low-and Middle-Income Countries (LMICs), Education, Health Managers Copyright: © 2015 by Kerman University of Medical Sciences Citation: Marrinan H, Firth S, Hipgrave D, Jimenez-Soto E. Let's take it to the clouds: the potential of educational innovations, including blended learning, for capacity building in developing countries.