2011
DOI: 10.1097/ta.0b013e3181fc93a2
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Early Appropriate Care: Definitive Stabilization of Femoral Fractures Within 24 Hours of Injury Is Safe in Most Patients With Multiple Injuries

Abstract: Early definitive stabilization is associated with acceptably low rates of complications and is safe in most patients with multiple injuries, including some with severe abdominal, chest, or head injuries with attention to resuscitation before surgery. More complications and longer hospital stay were noted with delayed fixation after adjusting for age and ISS. Chest injury was associated with pulmonary complications; however, the presence of severe abdominal injury was the greatest risk factor for complications.… Show more

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Cited by 97 publications
(79 citation statements)
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“…Although clinicians have rightfully focused on correspondence among head, chest, and abdominal injury with MOF, few studies have evaluated the impact and severity of pelvic trauma on the development of MOF [16,23]. ISS has long been used as a surrogate of mechanical injury; however, it has been shown to consistently underestimate mechanical injury [4,25].…”
Section: Discussionmentioning
confidence: 99%
“…Although clinicians have rightfully focused on correspondence among head, chest, and abdominal injury with MOF, few studies have evaluated the impact and severity of pelvic trauma on the development of MOF [16,23]. ISS has long been used as a surrogate of mechanical injury; however, it has been shown to consistently underestimate mechanical injury [4,25].…”
Section: Discussionmentioning
confidence: 99%
“…Повреждение медиаторами воспаления альвеоцитов и эндотелия легочных сосудов, капиллярный тромбоз приводят к нарушению проницаемости альвеоляр-но-капиллярного барьера, отеку легких, дыхательной недостаточности и инфекционным осложнениям [1]. Тяжелые повреждения груди с оценкой по шкале AIS, равной 2 баллам или более, при политравме с пере-ломами бедренной кости являются фактором риска развития ОРДС, пневмонии [14][15][16], сепсиса [17], ПОН [18] и смертельного исхода [19]. При этом ушиб лег-ких в большей степени влияет на течение иммунных реакций и риск системных осложнений политравмы [20].…”
Section: патофизиология взаимного отягощения скелетных и торакальных unclassified
“…Многие исследования свидетельствуют о том, что ранний, в первые 24 ч после получения политравмы, окончательный остеосинтез бедренной кости оказы-вает противошоковый эффект, позволяет в короткие сроки активизировать пострадавших и уменьшить частоту системных осложнений: синдрома жировой эмболии [11], ОРДС, пневмонии [15], сепсиса, ТЭЛА и ПОН [16,[30][31][32]. Кроме того, сокращаются продолжи-тельность искусственной вентиляции легких (ИВЛ), пребывания пациента в отделении интенсивной тера-пии и общий срок стационарного лечения, существен-но улучшаются анатомо-функциональные результаты лечения [32,33].…”
Section: ранний остеосинтез и феномен «второго удара»unclassified
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“…This includes patients with multiple injuries such as severe abdominal, chest, or head injuries as long as adequate attention has been paid to resuscitation and medical optimization prior to surgery. (Nahm, 2011) This optimization should include fluid resuscitation with crystalloid, colloid, and blood products as needed. The patient should be followed with serial arterial blood gas samples to follow the lactate levels and pH levels to show if the resuscitation is effective.…”
Section: Femur Fracturementioning
confidence: 99%