Early assessment of coronary flow reserve by transthoracic Doppler echocardiography predicts late remodeling in reperfused anterior myocardial infarction

Additional Prognostic Value of Coronary Flow Reserve in Diabetic and Nondiabetic Patients With Negative Dipyridamole Stress Echocardiography by Wall Motion Criteria

“…In addition, abnormal CFR was a strong predictor of death or worsening of clinical status in nonischemic dilated cardiomyopathy (50). Finally, CFR was predictive of ventricular remodeling-a recognized indicator of unfavorable outcome (51)-after acute myocardial infarction treated by primary angioplasty (52). In this study, there was no central reading.…”

Intravascular Imaging Tools in the Cardiac Catheterization Laboratory: Comprehensive Assessment of Anatomy and Physiology

“…Following baseline coronary blood flow measurements, hyperemic coronary velocity is measured following induction of coronary hyperemia with intravenous or intracoronary adenosine, adenosine triphosphate, papaverine, or selective adenosine 2A agonists [4]. Clinically, CFR has been used to assess the hemodynamic severity of intermediate coronary lesions (40-70% of diameter stenosis), to predict prognosis of coronary stent implantation, and to predict the recovery of ventricular wall motion and remodeling following infarction [5] and angioplasty [3]. More commonly, in patients with aniographically normal coronary vessels, CFR is used to assess the microvascular function.…”

Transthoracic Echocardiography in the Assessment of Coronary Arteries

“…According to the data of studies in patients with acute anterior myocardial infarction, CFVR is able to reflect an absence of microvascular reperfusion in the presence of a patent epicardial coronary artery, and is a negative determinant for myocardial viability (Ueno et al, 2002a;Rigo et al, 2004;Meimoun et al, 2009). Ueno et al, 2002a, reported that CFVR measured in open infarct-related LAD on day 1 after success primary angioplasty was a good predictor of the recovery of regional left ventricle function at discharge, whereas Rigo et al, 2004, found CFVR in the LAD <2.0 to be useful also in predicting an unfavorable longterm (6-month) outcome.…”

“…Ueno et al, 2002a, reported that CFVR measured in open infarct-related LAD on day 1 after success primary angioplasty was a good predictor of the recovery of regional left ventricle function at discharge, whereas Rigo et al, 2004, found CFVR in the LAD <2.0 to be useful also in predicting an unfavorable longterm (6-month) outcome. In the study of Meimoun et al, 2009, a cut-off CFVR value of 1.7 was an independent predictor of both the left ventricle recovery at a 3-month follow-up, and in-hospital adverse cardiac events including death, recurrent myocardial infarction, and acute heart failure.…”