Early clinical experience with the new amplatzer ductal occluder II for closure of the persistent arterial duct

Abstract

The ADO II is highly effective at providing rapid occlusion of morphologically varied PDAs. Occluder design allows closure with arterial or venous approach and delivery with 4 or 5 F delivery catheters. Stable occluder position is dependent on correct positioning of both aortic and pulmonary discs. A larger range of sizes and configurations of this occluder may be required to successfully occlude all ductal sizes and morphologies.

Early clinical experience with the new Amplatzer Ductal Occluder II for closure of the persistent arterial duct

“…We have demonstrated that percutaneous treatment with ADO2 can be realized with lower complication and residual shunt rates. The immediate and short term follow up success rate (complete occlusion) for duct occlusion by ADO2 at 24 hours, 7 days and 1 month was 97% respectively in our series which compares favourably with data reported using Amplazter ADO2 devices 7 . The multiple layers of nitinol allow for rapid ductal occlusion which reduces residual shunt risks.…”

“…The multiple layers of nitinol allow for rapid ductal occlusion which reduces residual shunt risks. The ability to position the ADO2 such that each of the retention discs assumes its independent orientation significantly reduces the risk of protrusion, anatomical distortion and displacement which has resulted in a 97% (n=31) success rate of device deployment in our series with only one (3%) re-intervention due to device dislodgement which compares favourably with reported data 7 .…”

“…Transcatheter closure procedures have been performed with high success rates both in children and adults [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] . Due to advances in diagnostic and therapeutic modalities diagnosis and treatment of PDA can be accomplished at a relatively early age [5][6][7] .…”

“…Due to advances in diagnostic and therapeutic modalities diagnosis and treatment of PDA can be accomplished at a relatively early age [5][6][7] . Thanopoulos et al 14 reported success rates of 95% and 98% soon after and one month after device implantation in patients with a mean age of 3.6 years.…”

“…Embolization during release of the device is one of the important complications of the procedure [7][8][9] . Embolization can occur in systemic and generally in pulmonary artery [7][8][9] .…”