1985
DOI: 10.1016/0002-9149(85)90375-3
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Early detection of restenosis after successful percutaneous transluminal coronary angioplasty by exercise-redistribution thallium scintigraphy

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Cited by 131 publications
(25 citation statements)
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“…Although the occurrence of restenosis in ‫ف‬ 20-55% of patients after clinically successful revascularization remains the major limitation to percutaneous transluminal coronary angioplasty (6)(7)(8)(9)(10)(11), no clinical trials have yet demonstrated convincing effects in reducing the incidence of restenosis (12)(13)(14). Previous studies using several models of angioplasty have demonstrated a rapid proliferative response of VSMCs in the media, followed by a second peak of proliferation in the neointima, which then declines to basal levels by 2-4 wk after angioplasty (15)(16)(17)(18).…”
Section: Introductionmentioning
confidence: 99%
“…Although the occurrence of restenosis in ‫ف‬ 20-55% of patients after clinically successful revascularization remains the major limitation to percutaneous transluminal coronary angioplasty (6)(7)(8)(9)(10)(11), no clinical trials have yet demonstrated convincing effects in reducing the incidence of restenosis (12)(13)(14). Previous studies using several models of angioplasty have demonstrated a rapid proliferative response of VSMCs in the media, followed by a second peak of proliferation in the neointima, which then declines to basal levels by 2-4 wk after angioplasty (15)(16)(17)(18).…”
Section: Introductionmentioning
confidence: 99%
“…Recent studies have suggested that percent diameter narrowing may not accurately reflect coronary flow reserve since flow is affected by other dimensions such as length and absolute radius (1-3). Accordingly, several investigators have suggested other criteria for successful angioplasty that rely on indirect measures of perfusion reserve (13)(14)(15)(16)(17)(18).…”
Section: Discussionmentioning
confidence: 99%
“…Several studies have reported that perfusion defects present before angioplasty resolve after successful an gioplasty (14,15). During follow-up periods up to 18 mo, Wijins et al found that 74% of patients with thallium perfusion defects that filled in at redistribution had re-stenosis at repeat arteriography ( 17).…”
Section: Discussionmentioning
confidence: 99%
“…Wijns et al analyzed the predictive values of stress test and thallium-201 scintigraphy performed 1 month after angioplasty in relation to clinical and angiographic findings at 6 months' 22 '. For angina, the predicitive values of stress test and thallium-201 scintigraphy were 38% and 66% and for restenosis 50% and 74%, respectively (/><0O05 in favour of thallium-201 scintigraphy).…”
Section: Non-invasive Detection Of Resteuosismentioning
confidence: 99%