Early development of GABA-like immunoreactive cells in the retina of turtle embryos

Versaux‐Botteri, Claudine; Hergueta, Stéphane; Pieau, Claude; Wasowicz, Marguerite Y; Dalil-Thiney, Najet; Nguyen‐Legros, Jeanine

doi:10.1016/0165-3806(94)90186-4

Cited by 14 publications

(12 citation statements)

References 30 publications

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“…2B). This early expression of GABA/GAD 67 by cells in the retina is supported elsewhere (Versaux-Botteri et al, 1994). In a less-developed region of the retina (in regions located farther from the optic nerve head), few cells showed GABA-/GAD 67 immunoreactivity and appeared to be in the process of migration (Fig.…”

Section: Descriptive Findingsmentioning

confidence: 93%

Colocalization of choline acetyltransferase and ?-aminobutyric acid in the developing and adult turtle retinas

Nguyen

Grzywacz

2000

J. Comp. Neurol.

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Acetylcholine and ␥ -aminobutyric acid (GABA) are putative neurotransmitters in the adult vertebrate retina. In this study, cells that coexpress choline acetyltransferase (ChAT) and GABA or glutamic acid decarboxylase (GAD) were investigated in turtle retinas from stage 14 (S14) to adulthood by using a double-labeling immunofluorescence technique. ChAT immunoreactivity was observed at S15 and included not only the presumptive starburst cholinergic amacrine cells but also a population in the ganglion cell layer (GCL) that expressed ChAT transiently during the embryonic stages (see the accompanying paper:

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Section: Descriptive Findingsmentioning

confidence: 93%

Colocalization of choline acetyltransferase and ?-aminobutyric acid in the developing and adult turtle retinas

Nguyen

Grzywacz

2000

J. Comp. Neurol.

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“…Neuroblastic GABAergic retinal cells have not been reported in other fish groups, but they were observed in the developing turtle and chick retinas before subdivision into nuclear or plexiform layers becomes apparent (Hokoç et al, 1990;Versaux-Botteri et al, 1994;Nguyen and Grzywacz, 2000). GABA is among the first neurotransmitters produced by the vertebrate retina (Messersmith and Redburn, 1993;Mitchell and Redburn, 1996), probably acting as a neurotrophic or signalling factor, promoting differentiation of neurons (Versaux-Botteri et al, 1994;Sandell et al, 1994;Buznikov et al, 1996). Moreover, in amphibians it has been demonstrated that some neuroblasts present in the neural plate and the neural fold acquire the ability to express the GABA phenotype during the early events of neurogenesis (Pituello et al, 1989).…”

Section: First Period (Stages 26-29): Gaba/gad In the Neuroblastic Rementioning

confidence: 97%

“…It has been proposed that GABA acts in the developing retina as a neurotrophic or signalling factor, promoting synaptogenesis, growth and differentiation of neurons (Versaux-Botteri et al, 1994;Sandell et al, 1994;Buznikov et al, 1996;Wang et al, 2007). However, the onset of the expression of GABA in retinal cells differs among vertebrates (Hokoç et al, 1990;Versaux-Botteri et al, 1994;Sandell et al, 1994;Negishi and Wagner, 1995;Hagedorn et al, 1998;Yamasaki et al, 1999;Nguyen and Grzywacz, 2000). Moreover, GABA has been implicated in the development and maturation of the outer retina because of its transient expression in horizontal cells (Schnitzer and Rusoff, 1984;Redburn and Madtes, 1987;Versaux-Botteri et al, 1989;Redburn, 1992, 1993;Pow et al, 1994;Fletcher and Kalloniatis, 1997;Yamasaki et al, 1999;Dkhissi et al, 2001;Loeliger and Rees, 2005).…”

Section: Introductionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

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Early development of GABAergic cells of the retina in sharks: An immunohistochemical study with GABA and GAD antibodies

Ferreiro-Galve

Candal

Carrera

et al. 2008

Journal of Chemical Neuroanatomy

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“…Gamma-aminobutyric acid (GABA) neurons appear early in the development of the embryonic central nervous system, including the retina (Lauder et al, 1986;Versaux-Botteri et al, 1994). Also, GABAA receptors are expressed in coincidence with its elevation in the brain (Cobas et al, 1991).…”

Section: Introductionmentioning

confidence: 99%

Taurine, glutamate and GABA modulate the outgrowth from goldfish retinal explants and its concentrations are affected by the crush of the optic nerve

1998

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The amino acid taurine plays an important trophic role during development and regeneration of the central nervous system. Other amino acid systems, such as those for glutamate and gamma-aminobutyric acid (GABA), are modified during the same physiological and pathological processes. After crushing the optic nerve, goldfish retinal explants were plated in the absence and in the presence of different amino acids and amino acid receptor agonists. The length and the density of the neurites were measured at 5 days in culture. Taurine increased the length and the density of neurites. Glutamate and glycine increased them at low concentration, but were inhibitors at higher concentration. The combination of N-methyl-D-aspartate (NMDA) and glycine produced a greater inhibitory effect than NMDA alone. NMDA or alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) added simultaneously with taurine impaired the stimulatory effect of the latter. GABA stimulated the emission of neurites in a concentration dependent manner. Hypotaurine also elevated the length of neurites, but cysteinsesulfinic acid did not produce a significant effect. The concentrations of taurine, glutamate and GABA were determined by HPLC with fluorescent detection in the retina of goldfish at various days post-crushing the optic nerve. The levels of taurine were significantly increased at 48h after the crush, and were elevated up to 20 days. Glutamate level decreased after the lesion of the optic nerve and was still low at 20 days. GABA concentration was not significantly different from the control. The interaction of these amino acids during the regenerative period, especially the balance between taurine and glutamate, may be a determinant in restoring vision after the crush.

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Early development of GABA-like immunoreactive cells in the retina of turtle embryos

Cited by 14 publications

References 30 publications

Colocalization of choline acetyltransferase and ?-aminobutyric acid in the developing and adult turtle retinas

Colocalization of choline acetyltransferase and ?-aminobutyric acid in the developing and adult turtle retinas

Early development of GABAergic cells of the retina in sharks: An immunohistochemical study with GABA and GAD antibodies

Taurine, glutamate and GABA modulate the outgrowth from goldfish retinal explants and its concentrations are affected by the crush of the optic nerve

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