Early diagnostic value of optical coherence tomography in the clinical prediction model for optic nerve injury in saddle space occupying patients

Liu, Weisheng; Zheng, Yuehua; Li, Yan; Cao, Peicheng; Zhou, Tao; Wang, Jinpeng; Li, Aijun

doi:10.1016/j.sjbs.2019.12.043

Cited by 1 publication

(1 citation statement)

References 16 publications

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“…As a result of ischemic optic nerve injury, retinal microvascular occlusion puts the optic nerve in a state of ischemia and hypoxia for a long time, and the optic nerves atrophy. Ischemic optic nerve injury is divided into optic nerve head injury and posterior optic nerve injury in accordance with the site of injury [ 54 , 55 , 56 ]. Acute optic nerve injury is more common in middle-aged and elderly people over the age of 50 [ 55 ].…”

Section: Introduction Of Optic Nerve Injury Ophthalmopathy and Animal...mentioning

confidence: 99%

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

et al. 2023

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Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness. These changes can cause alterations in protein expression within neurons in the retina. Proteomics analysis offers conclusive evidence to decode a biological system. Furthermore, animal models of optic nerve injury made it possible to gain insight into pathological mechanisms, therapeutic targets, and effective treatment of such injuries. Proteomics takes the proteome as the research object and studies protein changes in cells and tissues. At present, a variety of proteomic analysis methods have been widely used in the research of optic nerve injury diseases. This review summarizes the application of proteomic research in optic nerve injury diseases and animal models of optic nerve injury. Additionally, differentially expressed proteins are summarized and analyzed. Various optic nerve injuries, including those associated with different etiologies, are discussed along with their potential therapeutic targets and future directions.

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Section: Introduction Of Optic Nerve Injury Ophthalmopathy and Animal...mentioning

confidence: 99%

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

et al. 2023

View full text Add to dashboard Cite

show abstract

Early diagnostic value of optical coherence tomography in the clinical prediction model for optic nerve injury in saddle space occupying patients

Cited by 1 publication

References 16 publications

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

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