Early Enteral Nutrition Versus Parenteral Nutrition After Resection of Esophageal Cancer: a Retrospective Analysis

Abstract

This study aimed to compare the clinical outcomes and hospitalization cost between early enteral nutrition (EEN) and parenteral nutrition (PN) after resection of esophageal cancer. A total of 79 patients with esophageal cancer who underwent surgical treatment in our hospital from July 2010 to July 2013 were enrolled in this study. They were divided into EEN group (n=39) and PN group (n=40) based on the nutrition support modes. The clinical factors such as time to first fecal passage, postoperative albumin infusion, differences of serum albumin value, hospital stay, systematic inflammatory response syndrome (SIRS) duration, complications, initial hospitalization cost, and mortality were retrospectively compared. The EEN group had a significantly shorter hospital stay, lower initial hospitalization cost, earlier first fecal passage, and shorter duration of SIRS than PN group (P<0.05). The dose of albumin infusion was significantly smaller in EEN group (P<0.05) and the decreased value of serum albumin (Δalb) was more prominent in PN group compared with EEN group (P<0.05). The percentage of patients having any postoperative complication was much higher in PN group than EEN group (P<0.05), but there was no significant difference in in-hospital morbidity between two groups. Pneumonia was found significantly more frequent in PN group compared with EEN group (P<0.05). Early EN started within 48 h after esophagectomy is safe, economic, and superior for reduction of postoperative complication, for promoting early recovery of intestinal movement, and for early recovery from systemic inflammation.

Clinical effects of prophylactic transverse colostomy in patients undergoing completely laparoscopic transabdominal approach partial intersphincteric resection

“…Early enteral nutritional support can stimulate the secretion of gastrointestinal hormones and accelerate intestinal peristalsis, which facilitates the absorption of nutrients and rapid physical recovery after surgery. 29 The hospital stay was significantly shorter in Group A than in Group B (P ¼ 0.021), and the postoperative time to removal of the abdominal drain was 3 days earlier in Group A than in Group B (P ¼ 0.008). These results again confirm that prophylactic transverse colostomy has certain advantages and aligns with the concept of enhanced recovery after surgery.…”

Rehabilitation treatment of enteral nutrition whey protein in lung cancer patients in southern China

“…Chemotherapy can also cause stomatitis, sore throat, inflammation of the gastrointestinal mucosa, and liver dysfunction, aggravating the degree of malnutrition (Miyata et al, 2017;Debeljak et al, 2018;Yu et al, 2017;Chao et al, 2017). Some patients therefore refuse treatment or are forced to terminate treatment.…”

Early oral feeding after subtotal esophagectomy with immediate esophageal reconstruction as a component of ERAS protocol. A prospective randomized study

“…Согласно ряду исследований, после выполнения ЭЭ с одномоментной пластикой пищевода проведение ЭП является предпочтительным методом кормления в раннем послеоперационном периоде [22][23][24]. Однако в большинстве случаев проводить ЭП после ЭЭ рекомен-дуют через назоеюнальный зонд (НЕЗ) или еюностому (ЕС) [1,38].…”

“…Однако на протяжении последних лет все больше исследований рекомендуют проведение энтерального питания (ЭП) в раннем послеоперационном периоде [22][23][24], считая этот метод более безопасным и экономически выгодным по сравнению с ПП. ЭП не только поддерживает жизнеспособность энтероцитов и улучшает моторику желудочно-кишечного тракта (ЖКТ), но и обеспечивает сохранение кишечного барьера.…”