Early-life weight gain is associated with non-atopic asthma in childhood

Ho, Chia‐Hua; Gau, Chun‐Chun; Lee, Wan-Fang; Fang, Hsin; Lin, Ching‐Hua; Chu, Chun-Hui; Huang, Yin-Shan; Huang, Yunpeng; Huang, Hsin‐Yi; Tsai, Hui‐Ju; Yao, Tsung‐Chieh

doi:10.1016/j.waojou.2022.100672

Cited by 5 publications

(1 citation statement)

References 35 publications

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“…This study used the data collected from the Longitudinal Investigation of Global Health in Taiwanese Schoolchildren (LIGHTS) cohort, including 1513 children who were born in 2010 through 2011 in Chang Gung Memorial Hospital and who attended a follow-up visit at a mean age of 6.4 years, ranging from 5.5 to 7.9 years, as has been described elsewhere [21][22][23][24][25][26][27]. BMI and body fat percentages were measured during the follow-up visit between 2016 and 2018.…”

Section: Study Participantsmentioning

confidence: 99%

Maternal folic acid supplementation during pregnancy in association with childhood overweight or obesity

Hung,

Lee,

Tsai

et al. 2024

Obesity

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ObjectiveThis study aimed to examine associations of maternal folic acid supplementation (FAS) during pregnancy with childhood overweight or obesity (OWO) or adiposity.MethodsIn a population‐based cohort of 1479 children, maternal FAS during pregnancy was assessed retrospectively by questionnaires. BMI and body fat percentages were measured at a mean age of 6.4 years. Pertinent factors were accounted for in data analyses.ResultsMaternal FAS during pregnancy was negatively associated with OWO (adjusted odds ratio: 0.70; 95% CI: 0.50 to 0.99). There were inverse associations of maternal FAS during pregnancy with BMI z score (β: −0.22; 95% CI: −0.39 to −0.05), whole body fat percentage (β: −1.28; 95% CI: −2.27 to −0.30), trunk fat percentage (β: −1.41; 95% CI: −2.78 to −0.04), and limb fat percentage (β: −1.31; 95% CI: −2.32 to −0.30). Stratified analyses found inverse associations of FAS during pregnancy with OWO, BMI z score, and body fat percentages predominantly among children without breastfeeding and whose parents had a below‐tertiary educational level.ConclusionsThis study provides novel evidence that maternal FAS during pregnancy was significantly associated with a decreased risk of childhood OWO and adiposity, particularly among children with no breastfeeding and lower parental educational level.

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