Early Nonenhanced Abdominal Computed Tomography Can Predict Mortality in Severe Acute Pancreatitis

Spitzer, Austin L.; Thoeni, Ruedi F.; Barcia, Anthony M.; Schell, Michael T.; Harris, Hobart W.

doi:10.1016/j.gassur.2005.04.012

Cited by 17 publications

(10 citation statements)

References 45 publications

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“…Previous studies have also reported that the presence and degree of pancreas parenchyma morphology and peripancreatic inflammatory collections are closely correlated with the clinical course [13, 21, 22]. In our study, CT scans performed within 12 h of pain onset demonstrated that while patients with stage A and B disease showed no progression to stage E, a limited number of patients with stage C and D progressed.…”

Section: Discussionsupporting

confidence: 72%

“…Thus, absence of abnormal findings on CT performed within the first few hours does not exclude the possibility of AP [12]. Nevertheless, some studies have stated that CT performed early can predict changes in the course of AP [21, 22]. The study conducted by Munoz-Bongrand et al [13] found that, based on CT scans performed within the first hours of admission, no patient with stage A and B disease developed complications, and that the complication rate was significantly higher in patients with stage E compared to those with stage C and D disease.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Prediction of Self-Limited Acute Pancreatitis Cases at Admission to Emergency Unit

Kayar

Şentürk

Tozlu

et al. 2018

GE Port J Gastroenterol

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Background: While acute pancreatitis (AP) resolves spontaneously with supportive treatment in most patients, it may be life-threatening. Predicting the disease severity at onset dictates the management strategy. We aimed to define the patients with mild pancreatitis who may be considered for outpatient management with significant cost-savings. Materials and Methods: This prospective observational study included 180 patients with mild AP according to the harmless acute pancreatitis score (HAPS) and Imrie score. The relationships of biochemical parameters with the changes in the Balthazar score and clinical course were examined. Results: The study included 180 patients (111 females, 69 males; mean age: 53.9 ± 17.2 years; range: 17–92 years). The etiology was biliary in 118 (65%) patients and remained undetermined in 38 (21.1%) patients. Computed tomography (CT) performed within the first 12 h revealed mild and moderate AP in 159 (88.3%) and 21 (11.7%) patients, respectively. CT repeated at 72 h revealed mild, moderate, and severe AP in 155 (86.1%), 24 (13.3%), and 1 (0.6%) patients, respectively. Comparisons between stages A + B + C and D + E showed significant differences in the amylase levels on day 1 and 3, and in C-reactive protein on day 3. Also, in stage D and E disease, narcotic analgesic intake, oral intake onset time, and pain were significantly higher. Conclusion: There were no significant changes in the CT findings of patients with mild AP at 12 and 72 h. Most patients (n = 179; 99.4%) recovered uneventfully. Patients with mild pancreatitis according to the HAPS and Imrie scores can be considered for outpatient management. The recovery is longer in stage D and E disease.

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Section: Discussionsupporting

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Prediction of Self-Limited Acute Pancreatitis Cases at Admission to Emergency Unit

Kayar

Şentürk

Tozlu

et al. 2018

GE Port J Gastroenterol

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“…It divided patients into five classes (A-E) according to the anatomical changes of the pancreatic and peripancreatic tissues. The correlation with mortality was analysed in 7 studies [21,27,29,33,35,36,39] . Among them, three demonstrated a correlation between mortality and the five classes defined by the score [27,29,35] , two found an association when subject to univariate analysis [21,36] , one at multivariate analysis [21] and two used the ROC curves [33,39] .…”

Section: Radiological Scoresmentioning

confidence: 99%

Prediction of Mortality in Acute Pancreatitis: A Systematic Review of the Published Evidence

et al. 2009

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“…In patients with renal insufficiency or contrast allergies, a nonenhanced CT or MR can be performed. [26][27][28] Subtraction color maps may be helpful for diagnosing pancreatic necrosis in the early stages of acute pancreatitis (within first 72 hours). 29 …”

Section: Imaging Techniques Computed Tomographymentioning

confidence: 99%

Imaging of Acute Pancreatitis

Thoeni¹

2015

Radiologic Clinics of North America

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Early Nonenhanced Abdominal Computed Tomography Can Predict Mortality in Severe Acute Pancreatitis

Cited by 17 publications

References 45 publications

Prediction of Self-Limited Acute Pancreatitis Cases at Admission to Emergency Unit

Prediction of Self-Limited Acute Pancreatitis Cases at Admission to Emergency Unit

Prediction of Mortality in Acute Pancreatitis: A Systematic Review of the Published Evidence

Imaging of Acute Pancreatitis

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