2019
DOI: 10.1002/ana.25558
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Early results of nerve transfers for restoring function in severe cases of acute flaccid myelitis

Abstract: ObjectiveTo describe early functional outcomes of nerve transfer surgery in a relatively large cohort of patients with acute flaccid myelitis (AFM).MethodsA retrospective case analysis was made of patients with AFM treated with nerve transfer surgery between 2007 and 2018. Surgical criteria were persistent motor deficits after 6 months from onset and available donor nerves. Thirty‐two patients with AFM were evaluated; 16 underwent nerve transfer surgeries. Motor function was evaluated by a licensed occupationa… Show more

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Cited by 40 publications
(65 citation statements)
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“…Significant motor disability in acute flaccid myelitis children has led to interest in early nerve transfers to improve function. 15,16 Similar to the published case series, our study cohort had upper extremity nerve transfers performed using variable donor nerves depending on the proximity to the strong donor muscle-nerve pair. Rarely, the intercostal nerves were used as donor nerves.…”
Section: Discussionmentioning
confidence: 81%
“…Significant motor disability in acute flaccid myelitis children has led to interest in early nerve transfers to improve function. 15,16 Similar to the published case series, our study cohort had upper extremity nerve transfers performed using variable donor nerves depending on the proximity to the strong donor muscle-nerve pair. Rarely, the intercostal nerves were used as donor nerves.…”
Section: Discussionmentioning
confidence: 81%
“…Bracing must balance safety and use of the muscles. In addition, nerve and muscle transfer surgeries may be considered to maximize function in select patients 8 . AFM patients are at risk for secondary complications such as joint subluxation, limb length discrepancies, scoliosis, and decreased bone density 9 .…”
Section: Testing Recommendationmentioning
confidence: 99%
“…No treatment strategy currently exists for AFM patients but physical rehabilitation which, when implemented during the acute phase of the illness, slightly helps improve long-term neurological outcomes (Van Haren et al, 2015). Latest nerve transfer procedures also show promise in restoring partial function to paralyzed limbs in AFM patients (Pino et al, 2019).…”
Section: Acute Flaccid Paralysis and Acute Flaccid Myelitismentioning
confidence: 99%