2002
DOI: 10.1016/s1081-1206(10)61953-9
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Early sensitization to house dust mite is a major risk factor for subsequent development of bronchial asthma in Japanese infants with atopic dermatitis: results of a 4-year followup study

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Cited by 77 publications
(63 citation statements)
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“…The evidence that egg sensitization at the age of 1 year is predictive for later sensitization to inhalant allergen 19 has been confirmed in a recent article, 14 where patients already sensitized to egg white acquired specific IgE to mite sensitization in the follow-up period.…”
Section: Discussionmentioning
confidence: 81%
“…The evidence that egg sensitization at the age of 1 year is predictive for later sensitization to inhalant allergen 19 has been confirmed in a recent article, 14 where patients already sensitized to egg white acquired specific IgE to mite sensitization in the follow-up period.…”
Section: Discussionmentioning
confidence: 81%
“…12,13 An association between childhood atopic eczema and asthma has been shown in at least 1 cross-sectional study 14 and in several longitudinal studies. [15][16][17] A recent systematic review indicated that about 1/3 of children with atopic eczema before age 4 years will develop asthma by age 6 years or older. 18 The eczema/asthma association has been explained by invoking the atopic march [19][20][21] whereby children with eczema have a high risk of progression to asthma and/or allergic rhinitis later in childhood.…”
mentioning
confidence: 99%
“…In another study, the possibility of development of asthma in the future was calculated to be 70% in the presence of severe AD symptoms (8). In a study where 169 infants with AD were followed up for 4 years, 45% of the subjects showed asthma-like symptoms and 35% were diagnosed as asthma by a physician (23). When our patients in our study were examined in terms of development of additional allergic disease, it was found that 63 (55.2%) of 114 subjects developed additional allergic disease 23 of whom (20.2%) had asthma, 18 of whom (15.8%) had rhinitis and 22 of whom (19.3%) had asthma and rhinitis together and 51 subjects (44,7) did not develop any additional allergic disease.…”
Section: Discussionmentioning
confidence: 99%