Early Vertebroplasty versus Delayed Vertebroplasty for Acute Osteoporotic Compression Fracture : Are the Results of the Two Surgical Strategies the Same?

Son, Seong; Lee, Sang-Gu; Kim, Woo-Kyung; Park, Chanwoo; Yoo, Chan-Jong

doi:10.3340/jkns.2014.56.3.211

Cited by 24 publications

(25 citation statements)

References 15 publications

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“…[3,[6][7][8][9] In the present study, 14.5% of the 62 patients died of causes other than vertebral fractures or PVP within 1 year after treatment. One of reasons for the current relatively high mortality rate might be that we enrolled elder patients (mean age, >80 years); elderly individuals often have several preexisting diseases and, therefore, a high risk for mortality.…”

Section: Discussionmentioning

confidence: 88%

“…Previous investigations of patient QOL after PVP were evaluated with the following systems: Quality of Life Questionnaire of the European Foundation for Osteoporosis, Assessment of Quality of Life questionnaire, European Quality of Life, 5 Dimensions scale, Roland Morris Disability Questionnaire, Bartel Index, or Oswestry Disability Index [1,8,9]. These tests can comprehensively assess an individual's ADL proficiency including eating, dressing, moving, toileting, grooming, and bathing in addition to low back pain.…”

Section: Discussionmentioning

confidence: 99%

“…We excluded patients with vertebral fractures with non-osteoporotic causes, with an unclear onset date, or who frequently used a wheelchair before onset. We divided the 62 patients into Earlier and Later groups in which patients underwent PVP within 2 weeks (n = 46) or later (n = 16) after fracture onset, respectively [8,9].…”

Section: Patientsmentioning

confidence: 99%

“…Rather, prolonged bed rest due to vertebral facture requires monitoring because the bedridden state sometimes cause serious secondary disorders such as aspiration pneumonia, pulmonary thromboembolism, or disuse syndrome [4]. We speculated that the use of PVP might help avoid such diseases after osteoporotic vertebral fractures by facilitating an early recovery from back pain or ambulation difficulty [3,[5][6][7][8][9][10]. In the present study, we retrospectively investigated the effectiveness of PVP for patients who had difficulty walking due to acute osteoporotic vertebral fractures, and our analysis revealed that early treatment with PVP expedited the patients' recovery of ambulation, which is of clinical importance.…”

Section: Introductionmentioning

confidence: 99%

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Percutaneous Vertebroplasty for Acute Osteoporotic Vertebral Fracture Contributes to Restoration of Ambulation

Shida

Noguchi

Okafuji

et al. 2017

Interventional Radiology

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Purpose: To retrospectively determine the effectiveness of percutaneous vertebroplasty (PVP) for patients with ambulation difficulties due to acute osteoporotic vertebral fractures.Materials and Methods: We enrolled 62 patients who met the following criteria: almost normal ambulation before osteoporotic vertebral fracture, ambulation difficulties after onset, and a first-time PVP performed within 4 weeks. The patients were divided into Earlier (n = 46) or Later groups (n = 16) in which patients underwent PVP within 2 weeks or later, respectively. Mobility scores 7 days post-PVP in the Earlier group were compared with those 1 day before PVP in the Later group, that is, the conservatively waiting state. Earlier group values were also compared with those at 7 days post-PVP in the Later group to estimate the effectiveness of later PVP.Results: Mobility scores at 7 days post-PVP in Earlier group were significantly better than those 1 day before PVP in the Later group, suggesting that PVP provided mobility improvements sooner than the conservatively waiting state. Meanwhile, the lack of a difference in mobility scores at 7 days post-PVP between the Earlier and Later groups indicated that later PVP provided improvement comparable to earlier PVP.Conclusion: Earlier PVP contributes to earlier recovery from ambulation difficulties due to acute osteoporotic vertebral fractures than later PVP, while earlier and later PVP show equivalent efficacy in restoration of ambulation.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Patientsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Percutaneous Vertebroplasty for Acute Osteoporotic Vertebral Fracture Contributes to Restoration of Ambulation

Shida

Noguchi

Okafuji

et al. 2017

Interventional Radiology

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“…Die hier vorgestellte Studie an einer konsekutiven, repräsentativen Patientengruppe soll vor allem auch die Schmerzreduktion untersuchen. Es wurde für die Vertebroplastie bereits gezeigt, dass der Zeitpunkt des Eingriffs eine Auswirkung auf die Schmerzreduktion hat [11].…”

Section: Introductionunclassified

Der Zeitpunkt der Kyphoplastie beeinflusst das Ergebnis: eine prospektive Analyse

Trieb

Nittinger

2018

Sportverletz Sportschaden

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ZusammenfassungZiel der prospektiven Untersuchung war es, bei der Behandlung von Wirbelkörperfrakturen mittels Ballonkyphoplastie die Schmerzreduktion im Hinblick auf das Frakturalter zu evaluieren. Insgesamt konnten in dieser Studie 106 Patienten (37 männlich und 69 weiblich) mit 128 Wirbelkörperfrakturen mit einem mittleren Alter von 67,5 Jahren (21 bis 92 Jahre) bei einem Bodymaßindex von 26,4 (16–40,4) erfasst werden. Alle Frakturen wurden radiologisch und klinisch ausgewertet. Es wurden die Schmerzintensität (visuelle Analogskala 0–10), der Analgetikaverbrauch (WHO-Stufenschema 1 bis 3), der Oswestryscore und operationsrelevante Daten erhoben (Operationsdauer, Zementverbrauch, Komplikationen). Es wurden 37 A 1.1-, 43 A 1.2-, 43 A 1.3-, 4 A 3.1- und 1 A 2.3-Klassifikationen erhoben. Das Frakturalter in Tagen betrug bei 75 Patienten weniger als 23 Tage, die mittlere Operationszeit betrug 43 Minuten. Der Analgetikaverbrauch konnte von präoperativ 1,8 ± 0,8 auf 1,0 ± 0,6 reduziert werden. Eine signifikante Verbesserung zeigte sich in der Schmerzintensität; diese sank signifikant von 8,2 ± 0,9 präoperativ auf 3,9 ± 0,8 postoperativ. Bezogen auf das Frakturalter und die Schmerzintensität konnte eine deutlich höhere Schmerzreduktion bei den frischen Frakturen zwischen 0 und 23 Tagen erzielt werden. Hier sank die Schmerzintensität auf 2,5 ± 0,5 postoperativ, bei den später versorgten Frakturen lag dieser Wert bei 4,5 ± 0,4. Zusammenfassend kann festgestellt werden, dass die Ballonkyphoplastie eine suffiziente Methode ist Wirbelkörperfrakturen aufzurichten, den Kyphosewinkel zu verbessern und eine Schmerzreduktion zu erreichen.

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Percutaneous vertebroplasty for osteoporotic vertebral compression fracture

Buchbinder

Johnston

Rischin

et al. 2018

Cochrane Database of Systematic Reviews

138

126

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Based upon high- to moderate-quality evidence, our updated review does not support a role for vertebroplasty for treating acute or subacute osteoporotic vertebral fractures in routine practice. We found no demonstrable clinically important benefits compared with placebo (sham procedure) and subgroup analyses indicated that the results did not differ according to duration of pain ≤ 6 weeks versus > 6 weeks.Sensitivity analyses confirmed that open trials comparing vertebroplasty with usual care are likely to have overestimated any benefit of vertebroplasty. Correcting for these biases would likely drive any benefits observed with vertebroplasty towards the null, in keeping with findings from the placebo-controlled trials.Numerous serious adverse events have been observed following vertebroplasty. However due to the small number of events, we cannot be certain about whether or not vertebroplasty results in a clinically important increased risk of new symptomatic vertebral fractures and/or other serious adverse events. Patients should be informed about both the high- to moderate-quality evidence that shows no important benefit of vertebroplasty and its potential for harm.

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Early Vertebroplasty versus Delayed Vertebroplasty for Acute Osteoporotic Compression Fracture : Are the Results of the Two Surgical Strategies the Same?

Cited by 24 publications

References 15 publications

Percutaneous Vertebroplasty for Acute Osteoporotic Vertebral Fracture Contributes to Restoration of Ambulation

Percutaneous Vertebroplasty for Acute Osteoporotic Vertebral Fracture Contributes to Restoration of Ambulation

Der Zeitpunkt der Kyphoplastie beeinflusst das Ergebnis: eine prospektive Analyse

Percutaneous vertebroplasty for osteoporotic vertebral compression fracture

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