In a globalized world, national-level policymakers make decisions, often during times of crisis and uncertainty, which have implications for neighboring territories. Britain is an example of a nation state that has had to accommodate such a multi-level context in the management of crises. What is clear is that the processes of crisis management rely heavily on the effectiveness and strength of policy relationships at multiple levels of governance. Managing and coordinating crises in these contexts represents a challenge for national crisis managers as these complex governance landscapes produce uncertainties and can reveal ambiguities when it comes to identifying “who” is the dominant crisis manager. For example, the challenges of global health threats, such as the COVID-19 pandemic, highlight how modern governance arrangements breed vulnerabilities for states due to the interconnection of infrastructures and systems. The lack of clarity with regards to who is accountable for the performance of crisis management approaches within complex government environments open up windows of opportunity for blame and ideological games to take effect. Crisis management research highlights that the effectiveness of transnational crisis management depends on policy relationships within and between networks, including the extent to which national technocratic actors feature in the political decisions that affect crisis governance arrangements. Policy relationships themselves are also shaped by the contexts and dynamics of regional and territorial governance, Europeanization processes, and the internationalization of crisis management—all of which produce their own political tensions for the workings and autonomy of national crisis managers. Understanding such complexities is key for researching British crisis management processes.