2007
DOI: 10.1016/j.coph.2007.10.011
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Eating for pleasure or calories

Abstract: A changing environment and lifestyle on the background of evolutionary engraved or perinatally imprinted physiological response patterns is the foremost explanation for the current obesity epidemic. However, it is not clear what the mechanisms are by which the modern environment overrides the physiological controls of appetite and homeostatic body weight regulation. Major advances have been made regarding cross talk between metabolic signals and the cognitive/emotional brain that primarily deals with the envir… Show more

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Cited by 97 publications
(63 citation statements)
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“…Leptin and insulin are two nutritionally relevant hormones involved in modulating the "wanting" of food; both can act directly on mesolimbic dopamine neurons (Zheng and Berthoud, 2007).…”
Section: Food Rewardmentioning
confidence: 99%
“…Leptin and insulin are two nutritionally relevant hormones involved in modulating the "wanting" of food; both can act directly on mesolimbic dopamine neurons (Zheng and Berthoud, 2007).…”
Section: Food Rewardmentioning
confidence: 99%
“…Traditionally, the mechanisms for regulating feeding were concerned with only the hypothalamic neural pathways and ventromedial nucleus (Saper et al, 2002;Shin et al, 2009;Zheng and Berthoud, 2007). Research within the last ten years, however, has realized a more complex system also involving the engagement of the caudal brainstem, the senses and the cortico-limbic system (Shin et al, 2009;Zheng and Berthoud, 2007).…”
Section: Food Intake Regulationmentioning
confidence: 99%
“…Research within the last ten years, however, has realized a more complex system also involving the engagement of the caudal brainstem, the senses and the cortico-limbic system (Shin et al, 2009;Zheng and Berthoud, 2007).…”
Section: Food Intake Regulationmentioning
confidence: 99%
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