Eccrine cylindroma of the ear canal – report of a case

Sharma, Hari Shankar; Meorkamal, M. Z.; Zainol, H.; Dharap, A. S.

doi:10.1017/s0022215100127902

Cited by 8 publications

(3 citation statements)

References 6 publications

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“…Sometimes, a solitary cylindroma, or groups, can cover the eyes 25,31 . Furthermore, discomfort, pain, hearing loss, and deafness may be the result of tumor growth into the external ear, with occlusion of the auditory canal, as observed in our patient 25–28 . As described previously in other patients, the unilateral hearing loss resolved after surgical excision of the cylindroma occluding the meatus externus in the external auditory canal.…”

Section: Discussionsupporting

confidence: 82%

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Brooke–Spiegler syndrome complicated by unilateral hearing loss

et al. 2008

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Brooke-Spiegler syndrome is an autosomal dominant tumor predisposition disorder. The disease is characterized by the occurrence of multiple skin appendage tumors, including cylindroma, trichoepithelioma, and spiradenoma. In some patients, tumors cover the entire head circumference, thereby causing disfigurement and other complications. Here, we report on a man with multiple cylindroma that were distributed in a turban tumor-like fashion. One of these neoplasms arose in the meatus externus of the right ear leading to unilateral hearing loss, a complication that has been documented only on few occasions in this disease.

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Section: Discussionsupporting

confidence: 82%

“…In this article, we report a patient with the characteristic phenotype of turban tumor syndrome and unilateral hearing loss caused by tumor growth in the ear. This complication has only been documented on a few occasions in BSS 25–28 …”

Section: Introductionmentioning

confidence: 99%

Brooke–Spiegler syndrome complicated by unilateral hearing loss

et al. 2008

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“…Pain is a characteristic symptom suggesting malignancy [1,5,7]. Hearing loss and secondary otitis externa may be present according to the site and extension of the mass.…”

Section: Discussionmentioning

confidence: 99%

Recurrent Ceruminous Adenocarcinoma of the External Auditory Canal

Tzagaroulakis¹,

Pasxalidis²,

Papadimitriou³

et al. 2003

ORL

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Ceruminous adenocarcinoma is a rare malignant neoplasm of the glandular structures of the external auditory canal. The true incidence and behavior of these rare tumors are still unclear due to confusing terminology, classification and histological definitions. Therefore, the ENT surgeon faces major difficulties in choosing the method of management – conservative or more radical surgery – with the addition or not of radiotherapy. We report a 57-year-old male patient with a recurrence of a previously excised (maybe partially) and irradiated ceruminous adenocarcinoma of the right external auditory canal. Aggressive surgery was considered as the treatment of choice. However, the patient refused this approach and, as a consequence, a conservative excision was performed but with histologically confirmed healthy margins. To our surprise, the patient showed an excellent response and he is disease free 3 years following the last operation. Although recurrences usually occur within months after inadequate management, some may happen even 7 years post treatment. Therefore, routine long-term follow-up was advised.

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Ceruminous Gland Carcinomas: A Clinicopathologic and Immunophenotypic Study of 17 Cases

Crain

Nelson

Barnes

et al. 2008

Head and Neck Pathol

103

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Background Ceruminal gland carcinomas are rare neoplasms confined to the skin lining the cartilaginous part of the external auditory canal. Design Retrospective. Results The patients included 11 men and 6 women, aged 33–82 years (mean, 59.5 years). Patients presented clinically with a mass of the outer half of the external auditory canal (n = 14), hearing changes (n = 5), drainage (n = 4), or paralysis of the facial nerve (n = 3). The polypoid masses ranged in size from 0.5 to 3 cm in greatest dimension (mean, 1.8 cm). Histologically, the tumors demonstrated a solid to cystic pattern, composed of an infiltrating glandular to cribriform arrangement of epithelial cells. Histologic features included a dual cell population (although not the dominant histology), increased cellularity, moderate to severe nuclear pleomorphism, irregular nucleoli, increased mitotic figures (mean, 3/10 HPF), including atypical forms, and tumor necrosis (n = 2). Tumors were divided into three types of adenocarcinoma based on pattern of growth and cell type (ceruminous, NOS [n = 12], adenoid cystic [n = 4], mucoepidermoid [n = 1]). CK7 and CD117 highlighted the luminal cells, while S1-00 protein showed a predilection for the basal cells of ceruminous and adenoid cystic carcinomas. Metastatic adenocarcinoma or direct extension from salivary gland neoplasms are the principle differential considerations. Surgical resection was used in all patients with radiation used in four patients. Eleven patients were alive or had died of unrelated causes without evidence of disease (mean, 11.2 years); six patients had died with disease (mean, 4.9 years), all of whom had developed local recurrence. Conclusion Ceruminous-type carcinomas, with the exception of ceruminous mucoepidermoid carcinoma, all demonstrated a dual cell population of basal myoepithelial-type cells and luminal apocrine cells. The specific histologic sub-type does not influence the long-term patient outcome.

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Eccrine cylindroma of the ear canal – report of a case

Cited by 8 publications

References 6 publications

Brooke–Spiegler syndrome complicated by unilateral hearing loss

Brooke–Spiegler syndrome complicated by unilateral hearing loss

Recurrent Ceruminous Adenocarcinoma of the External Auditory Canal

Ceruminous Gland Carcinomas: A Clinicopathologic and Immunophenotypic Study of 17 Cases

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