Eccrine porocarcinoma on the cheek

Abstract

Eccrine porocarcinoma is a rare malignant tumor arising from the intraepidermal ductal portion of the eccrine sweat gland. It develops either spontaneously or from a long standing benign eccrine poroma. This entity usually affects older people and is commonly located on the lower extremities, the trunk, and the head. We report a case of eccrine porocarcinoma on the left cheek in an 85-year-old male. In our case, the tumor was treated with wide excision and postoperative adjuvant radiation therapy. The patient recovered well without local recurrence and distant metastasis during the 14-month follow-up period. Wide excision and postoperative adjuvant radiation therapy can be considered as a safe and effective treatment option in treating patients with eccrine porocarcinoma.

Eccrine porocarcinoma of the head and neck: Meta‐analysis of 120 cases

“…Staining of CEA and EMA typically are positive whereas S‐100 is negative in intraepidermal ductal cell. Conversely, S‐100 staining is positive in myoepithelial cells of glandular portions 21,23,79 . In our meta‐analysis, EMA and/or CEA were described in 30.8% and 40.0% of patients, respectively.…”

“…The remaining 116 EPC cases of the head and neck from 90 studies were included in the meta‐analysis. The studies consist of 77 single case reports 7‐14,21,25‐93 and 13 case series with an average of three cases 20,23,24,94‐103 . Additionally, four EPC cases of the University Hospital of the Medical University of Vienna and Evangelical Hospital Vienna could be included in the meta‐analysis.…”

Eccrine Porocarcinoma: A Multicenter Retrospective Study with Review of the Literatures Reported in Korea

“…In this study, only three patients received chemotherapy, which was administered as an initial management (combination of 5-fluorouracil and cisplatin) 19 , adjuvant chemotherapy (5-FU) 6 , or management after the recurrence and metastasis (5-FU→adriamycin→paclitaxel) 18 . Radiation therapy was used as an adjuvant therapy 7,17,18 , for palliative care 18,24 , or for management of regional lymph node metastasis 11 .…”

Poroid hidradenoma of the scalp

“…Despite the lack of reported malignancy with poroid hidradenoma, it can be developed to eccrine porocarcinoma as a primary lesion and be misdiagnosed with a malignant subcutaneous neoplasm and excised with a skin sparing procedure [ 6 ]. Further, it is not yet known whether additional safety margins should be used during excision.…”