Echinococcus equinus and Echinococcus granulosus sensu stricto from the United Kingdom: genetic diversity and haplotypic variation

Boufana, Belgees; Lett, Wai San; Lahmar, Samia; Buishi, Imad; Bodell, A.J.; Varcasia, Antonio; Casulli, Adriano; Beeching, Nicholas J.; Campbell, Fiona; Terlizzo, Monica; McManus, Donald P.; Craig, Philip S.

doi:10.1016/j.ijpara.2014.10.005

Cited by 48 publications

(43 citation statements)

References 38 publications

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“…Boufana and colleagues [12][13][14][15] based on previous research [16,17], many of the new haplotypes that were identified here would have been overlooked. As previously mentioned, there is a clear difference in the outcomes of an investigation of genetic diversity of E. granulosus s.s. according to the length of the gene analysed [8,10].…”

Section: Additionally Had the Analysis Been Based On The 827 Sectionmentioning

confidence: 82%

High intraspecific variability of Echinococcus granulosus sensu stricto in Chile

Rojas

Ebi

Paredes

et al. 2017

Parasitology International

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Echinococcus granulosus sensu stricto is the major cause of cystic echinococcosis in most human and animal cases in the world and the most widespread species within the E. granulosus sensu lato complex. E. granulosus s.s. remains endemic in South America together with other species of the Echinococcus genus, especially in some areas in Argentina, Brazil, Chile and Peru. Except for a single human case caused by E. canadensis (G6) described in the literature, only E. granulosus s.s. has been found in the Chilean territory. In the current study 1609bp of the cox1 gene from 69 Chilean isolates of E. granulosus s.s. from humans and animals were analysed. In total, 26 cox1 haplotypes were found, including the widespread haplotype EG01 (22 isolates) and also EGp1 (5), EgRUS7 (1), EgAus02 (1) and EgAus03 (2). Twenty-one different haplotype not previously described were identified from 38 Chilean isolates designated EgCL1-EgCL21. Previous work had described low variability of E. granulosus s.s. in South America, based on isolates from Peru. Results obtained in this work challenge the previously described idea of the low diversity of the parasite in South America, and warrant future investigation on the origin and spread of the parasite in the continent after the Spanish arrival.

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Section: Additionally Had the Analysis Been Based On The 827 Sectionmentioning

confidence: 82%

High intraspecific variability of Echinococcus granulosus sensu stricto in Chile

Rojas

Ebi

Paredes

et al. 2017

Parasitology International

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“…8 and Table S7 in the Supplementary Material). However, in the UK E. granulosus (G1-G3) has been found in dogs, sheep and cattle whilst E. equinus (G4) has been isolated from horses, dogs and from two captive mammals zebra (Equus burchellii) and lemur (Varecia rubra) (Boufana et al, 2015b). In Ireland, E. equinus has been found in horses and dogs (Hatch, 1970;Kumaratilake et al, 1986).…”

Section: U N C O R R E C T E D P R O O Fmentioning

confidence: 99%

Global Distribution of Alveolar and Cystic Echinococcosis

Deplazes

Rinaldi

Rojas

et al. 2017

Advances in Parasitology

774

679

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“…Laurimaa et al, from the Zoology Department of the Institute of Ecology and Earth Sciences at the University of Tartu, Estonia, studied fecal sample from 181 stray dogs in an urban area of Estonia in 2012-13, reporting positivity for EG in 2.2 % of the cases, with sequencing for the G1 genotype (positivity was not verified for E. multilocularis). Boufana et al (2015) of the Ecosystems and Environment Research Centre at the University of Salford, UK and other related centers, studied hydatid cysts isolated in horses, cysts recovered from mammals in captivity, and coproDNA from hunting dogs and farm dogs, identifying E. equino from the horse samples, EG (S. S.) in cattle and sheep samples and from farm dog feces. A variation in the haplotypes of EG (S. S.) was detected in the COI sequences (Boufana et al).…”

Section: Available Evidencementioning

confidence: 99%

Molecular Epidemiology of Cystic Echinococcosis: Genotypic Characterization in Humans and Different Livestock

Manterola

Otzen

2016

Int. J. Morphol.

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SUMMARY:Echinococcus Granulosus (EG) is the major cause of cystic echinococcosis in humans and livestock in the world. In Chile is a zoonosis of great importance. The most frequently affected geographic areas are the Regions of Aysén, Los Rios, Los Lagos, Coquimbo and the Araucanía. Hence, it was discovered that in endemic areas of hydatidosis there could be several strains and genotypes of EG. In addition, there is evidence that some strains and genotypes are more infectious for human beings than others. This interesting phenomenon of the biology of EG has been studied using molecular biology techniques based on polymerase chain reaction (PCR) and DNA sequence analysis, which has made it possible to characterize the cestode species complex called EG sensu lato (s l) as being comprised of EG sensu stricto (s.s.) (Genotypes G1-G3), E. equinus (G4), E. ortleppi (G5) and E. canadensis (G6-G10), which present an important phenotypic variation detectable in characteristics of the biological cycle, specificity of the intermediate host, pattern of development, pathogenicity, antigenicity, transmission dynamics and, consequently, in the measures needed to control the disease. The aim of this manuscript is to describe the different genotypes of EG described in humans and different livestock host reported in the literature.

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Echinococcus equinus and Echinococcus granulosus sensu stricto from the United Kingdom: genetic diversity and haplotypic variation

Cited by 48 publications

References 38 publications

High intraspecific variability of Echinococcus granulosus sensu stricto in Chile

High intraspecific variability of Echinococcus granulosus sensu stricto in Chile

Global Distribution of Alveolar and Cystic Echinococcosis

Molecular Epidemiology of Cystic Echinococcosis: Genotypic Characterization in Humans and Different Livestock

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