Echocardiographic evaluation of epicardial adipose tissue in non-diabetic, non-hypertensive hemodialysis patients

Abstract

Turkey AbstractPurpose: It has been found out that the epicardial adipose tissue (EAT) measured by echocardiography is related with various metabolic parameters. Being accepted as the new cardiovascular risk indicator, there have been few studies on EAT in relation to the patients with end-stage renal failure. In our study, we aim to evaluate EAT and carotid intima media thickness (CIMT) in non-diabetic, non-hypertensive hemodialysis (HD) patients. Methods: Our study recruited 47 non-diabetic, non-hypertensive HD patients (22 males, 25 females, median age 54 (44.3-60.8) years) and an age-gender matched control group consisting 41 healthy subjects (17 males, 24 females, median age 52 (48-56) years). In all patients, EAT was measured by echocardiography and CIMT by ultrasonography; and routine laboratory parameters were studied. Results: In our study, we obtained laboratory findings matching with the profiles of uremic patients among HD patients and CIMT values of HD patients are significantly higher than that of the control group

The Association of Glomerular Filtration Rate With Echocardiographic Parameters in Chronic Kidney Disease

“…They found that stage IV and V patients had higher epicardial fatty vol-umes compared to the controls [28]. Despite this, Ozkurt et al showed that EFT was similar in CKD patients and controls [29]. In our study, we found that stage IV and V subjects had the higher EFT, which is consistent with a meta-analysis by Song et al [27].…”

Epicardial Adipose Tissue Thickness in Hemodialysis Patients

“…Some studies demonstrated an increase in EAT thickness by MSCT in patients with PD and HD, 8,9 while in another study, EAT thickness acquired by echocardiography in patients with HD was similar to control subjects. 29 In our study, we found that EAT thickness was higher in HD patients and was correlated with CIMT used for detecting early atherosclerosis, as similar to other studies. 16,30 Consistent with other studies, correlations between EAT thickness and cardiovascular risk factors (age, calcium) were also presented in our study.…”

“…Until now, studies have reported conflicting results about EAT thickness in receiving HD and PD patients. Some studies demonstrated an increase in EAT thickness by MSCT in patients with PD and HD,while in another study, EAT thickness acquired by echocardiography in patients with HD was similar to control subjects . In our study, we found that EAT thickness was higher in HD patients and was correlated with CIMT used for detecting early atherosclerosis, as similar to other studies .…”

Relationship Between Epicardial Adipose Tissue, Inflammation and Volume Markers in Hemodialysis and Transplant Patients

“…However, there are little data about the association of EAT and clinical parameters in an end‐stage renal disease (ESRD) population . Unfortunately, there are no data in the literature about EAT thickness of the Rtx patients in the post‐transplantation period.…”