Echocardiographic Features of Congestive Cardiomyopathy Compared with Normal Subjects and Patients with Coronary Artery Disease

Corya, Betty C.; Feigenbaum, Harvey; Rasmussen, S; Black, Mary Jo

doi:10.1161/01.cir.49.6.1153

Cited by 89 publications

(11 citation statements)

References 28 publications

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“…12 To determine whether the contraction pattern on cine CMR could establish the cause of the heart failure in our cohort, patients were labeled as having regional or global dysfunction. Regional dysfunction was defined when the maximum minus the minimum wall motion score for a given patient was Ն3.…”

Section: Regional Versus Global Dysfunctionmentioning

confidence: 99%

Gadolinium Cardiovascular Magnetic Resonance Predicts Reversible Myocardial Dysfunction and Remodeling in Patients With Heart Failure Undergoing β-Blocker Therapy

Bello

Shah

Farah³

et al. 2003

Circulation

309

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Background-In some patients with heart failure, ␤-blockers can improve left ventricular (LV) function and reduce morbidity and mortality. We hypothesized that gadolinium-enhanced cardiovascular magnetic resonance imaging (CMR) can predict reversible myocardial dysfunction and remodeling in heart failure patients treated with ␤-blockers. Methods and Results-Forty-five patients with chronic heart failure underwent CMR. Contrast imaging using gadolinium was performed to obtain high-resolution spatial maps of myocardial scarring and viability. Cine imaging was performed to assess LV function and morphology and was repeated in 35 patients after 6 months of ␤-blockade. Gadolinium CMR demonstrated scarring in 30 of 45 patients (67%). Scarring was found in 100% of patients with ischemic cardiomyopathy (28 of 28) but in only 12% with nonischemic cardiomyopathy (2 of 17). In the 35 patients who were maintained on ␤-blockers and had a second study, there was an inverse relation between the extent of scarring at baseline and the likelihood of contractile improvement 6 months later (PϽ0.001). For instance, contractility improved in 56% (674 of 1207) of regions with no scarring but in only 3% with Ͼ75% scarring (8 of 232). Multivariate analysis showed that the amount of dysfunctional but viable myocardium by CMR was an independent predictor of the change in ejection fraction (Pϭ0.01), mean wall motion score (Pϭ0.0007), LV end-diastolic volume index (Pϭ0.007), and LV end-systolic volume index (PՅ0.0001). Conclusions-For

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Section: Regional Versus Global Dysfunctionmentioning

confidence: 99%

Gadolinium Cardiovascular Magnetic Resonance Predicts Reversible Myocardial Dysfunction and Remodeling in Patients With Heart Failure Undergoing β-Blocker Therapy

Bello

Shah

Farah³

et al. 2003

Circulation

309

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show abstract

“…In addition, several investigators have attempted to define the features that might be useful in distinguishing echocardiograms of patients with congestive cardiomyopathy from those of patients with Coronary artery disease [1,5,7,9,15,17]. The common echocardiographic characteristics of congestive cardiomyopathy include increased left ventricular dimensions, reduced excursion of both the Septum and left ventricular posterior wall, deCreased velocity of circumferential fiber shortening (Vcf), and posterior displacement of the mitral Valve.…”

Section: Discussionmentioning

confidence: 99%

“…The common echocardiographic characteristics of congestive cardiomyopathy include increased left ventricular dimensions, reduced excursion of both the Septum and left ventricular posterior wall, deCreased velocity of circumferential fiber shortening (Vcf), and posterior displacement of the mitral Valve. Corya et al [5] and Feigenbaum [9], in attempting to distinguish cardiomyopathy from coronary artery disease, reported that in patients with cardiomyopathy, there is diffuse involvement of the entire left ventricle. In patients with coronary artery disease, including those in congestive heart failure, left ventricular involvement may be segmental.…”

Section: Discussionmentioning

confidence: 99%

Echocardiography in infants with anomalous origin of the left coronary artery

Shapiro

Krongrad

1979

Pediatr Cardiol

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Anomalous origin o f the left c o r o n a r y artery from the p u l m o n a r y artery is a rare congenital heart defect accounting for less than 0.5% o f patients with COngenital heart disease [3]. Early diagnosis is important for optimal medical and surgical management. Traditionally, the triad of congestive heart failure, significant cardiomegaly without a murmur, and electrocardiographic evidence o f ischemia or infarction has strongly suggested the diagnosis of rted in part by Research Fellowship Award 1 F32 HL-05675-01~ and by research grant HL-12738-092 from the National Heart, Lung, and Blood Institute, United States Public Health Service.Address reprint requests to: Ehud Krongrad, MD, Department of Pediatrics, Columbia Presbyterian Medical Center, 3975 Broadway (BHA 1-102), New York, NY 10032, USA Materials and MethodsClinical Data. Observations were made in four infants who were referred for cardiac evaluation to Babies Hospital, Columbia Presbyterian Medical Center. The initial clinical and pertinent cardiac catheterization data are given in Table 1. All the patients were in severe congestive heart failure. Only one infant had an apical murmur of mitral insufficiency. Chest x-ray films showed striking cardiomegaly and pulmonary vascular congestion.The presenting electrocardiogram was abnormal in all four patients. Common features were deep Q-waves in leads 1 and AVL and signs of left ventricular ischemia or infarction. In addition, there was evidence of left ventricular conduction delay with a QRS duration of 0.08 to 0.09 sec. and a slurred or notched upstroke of the R wave in V5 and V6 in each case. The electrocardiogram from patient 2 is representative (Fig. 1). Echocardiograms were performed at the time of initial evaluation.Cardiac catheterizations were also performed, and the diagnosis of anomalous left coronary artery arising from the pulmonary artery was confirmed in each patient. Left ventricular function was uniformly impaired with high left ventricular end-diastolic pressures and markedly decreased ejection fractions. A left-to-0172-0643/79/0001-0023 $01.20

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“…The left ventricular end-systolic dimension (LVES) was measured as the shortest recorded distance between the left ventricular septal and posterior wall endocardial echo. The thicknesses ofthe septum and of the left ventricular posterior wall were measured as previously described by Corya et al, 1974b. The percentage fractional shortening of the left ventricular dimension (%FSLV) was calculated as follows:…”

Section: Methodsmentioning

confidence: 99%

Echocardiographic assessment of left ventricular function in coronary arterial disease.

Chandraratna¹,

Rashid²,

Tolentino³

et al. 1977

Heart

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Echocardiographic Features of Congestive Cardiomyopathy Compared with Normal Subjects and Patients with Coronary Artery Disease

Abstract: SUMMARYEchocardiograms of ten patients with congestive cardiomyopathy were compared to those of three groups of patients: (1) 17

Cited by 89 publications

References 28 publications

Gadolinium Cardiovascular Magnetic Resonance Predicts Reversible Myocardial Dysfunction and Remodeling in Patients With Heart Failure Undergoing β-Blocker Therapy

Gadolinium Cardiovascular Magnetic Resonance Predicts Reversible Myocardial Dysfunction and Remodeling in Patients With Heart Failure Undergoing β-Blocker Therapy

Echocardiography in infants with anomalous origin of the left coronary artery

Echocardiographic assessment of left ventricular function in coronary arterial disease.

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