Echovirus Type 7 Meningitis in Young Children

Jarvis, William R.; Tucker, Grace

doi:10.1001/archpedi.1981.02130350013006

Cited by 10 publications

(6 citation statements)

References 14 publications

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“…At the beginning of the 1980s, Javirs and Tucker (9) reported one case of AM caused by E-7 in young children. During the surveillance of viral infections of the central nervous system in Finland in late 1985, E-5 was recognized as the most important etiological agent of an AM outbreak (11).…”

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confidence: 99%

Echovirus 6 associated to aseptic meningitis outbreak, in São Joaquim da Barra, São Paulo, Brazil

Luchs

Russo

Cilli

et al. 2008

Braz. J. Microbiol.

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An aseptic meningitis outbreak occurred during a period from February to May 2004 in São Joaquim da Barra, a town in the northern region of São Paulo State. A total of 40 cases were reported to the Epidemiological Surveillance Center of São Paulo State. Cerebrospinal fluid samples obtained from 23 patients were sent to the Adolfo Lutz Institute for isolation of the virus. These samples were inoculated into RD, HEp2 and Vero cell lineages and those presenting a cytopathogenic effect were selected for analysis by indirect immunofluorescence assay (IFA), neutralization testing (Nt) and reverse transcriptase-polymerase chain reaction (RT-PCR). Cytopathogenic effects were observed in 52.2% (12/23) of these samples. All isolated viruses were identified as human enterovirus by IFA and RT-PCR and echovirus 6 was typed by IFA and Nt. Our results confirmed the participation and importance of echovirus as the etiological agent responsible for this outbreak and the serotype diversity of human enteroviruses circulating in São Paulo State.

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confidence: 99%

Echovirus 6 associated to aseptic meningitis outbreak, in São Joaquim da Barra, São Paulo, Brazil

Luchs

Russo

Cilli

et al. 2008

Braz. J. Microbiol.

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“…CSF pleocytosis associated with isolation of an enterovirus from a nOn-CSF site is used to make a presumptive diagnosis of enteroviral meningitis (Farmer et al 1975, Singer et al 1980, Jarvis et al 1981, Wilfert et al 1981, Sumaya et al 1982, Wildin and Chonmaitree 1987, Dagan et al 1988). The validity of establishing the diagnosis of CNS enteroviral infection based on these findings has not been carefully examined.…”

Section: Discussionmentioning

confidence: 99%

“…When an enterovirus is isolated from a non-CSF site (Le. rectum, throat, nasopharynx, blood) in conjunction with CSF pleocytosis and absence of bacterial pathogens, enteroviral meningitis is the presumptive diagnosis (Farmer et al 1975, Singer et al 1980, Jarvis and Tucker 1981, Wilfert et al 1981, Sumaya andCorman 1982, Wildin andChonmaitree 1987, Dagan ef al. 1988).…”

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Suspect Value of Non‐csf Viral Cultures in the Diagnosis of Enteroviral CNS Infection in Young Infants

Johnson

McAbee

Seaton

et al. 1992

Develop Med Child Neuro

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SUMMARY Laboratory criteria used for presumptive diagnosis of enteroviral meningitis were evaluated as predictors of cerebrospinal fluid (CSF) infection. Records were retrospectively analysed of infants under four months of age admitted to hospital between 1977 and 1987 with viral CSF cultures: those with enteroviruses isolated from CSF (group 1) were compared with those with enteroviruses isolated only from non CSF sites (group 2). Predictive value computations demonstrated that no single or combined non‐CSF culture accurately predicted isolation of enteroviruses from the CSF. These results suggest that CSF viral culture is imperative in establishing the diagnosis of enteroviral meningitis in young infants. RÉSUMÉ Valeur de cultures virales hors LCR dans le diagnostic des infections à enterovirus du SNC, chez le nourrisson Les critères de laboratoire utilisés pour une présomption diagnostique de méningite à entérovirus ont étéévalués dans leur capacitéà prédire une infection du liquide céphalo‐rachidien (LCR). Les dossiers de nourrissons âgés de moins de quatre mois, admis à l'hôpital entre 1977 et 1987, avec culture virale du LCR, furent analyses rétrospectivement: une comparaison fut faite entre un groupe 1 avec entérovirus isolé dans le LCR et un groupe 2 avec entérovirus isolés seulement hors LCR. Les calculs de valeur prédictive (PV) démontrèrent qu'aucune culture isolée ou combinée, hors LCR, prédisait correctement l'isolement d'entérovirus dans le LCR. Ces résultats suggèrent que la culture virale du LCR est impérative pour établir le diagnostic de méningite à entérovirus chez le nourrisson. ZUSAMMENFASSUNG Welchen Wert haben Viruskulturen von nicht‐Liquor Material für die Diagnose einer Infektion des Zentralnervensystems durch Enteroviren bei Säuglingen Laborwerte, die zur Verdachtsdiagnose einer enteroviralen Meningitis führten, wurden auf ihre Aussagekraft hinsichtlich einer Liquorinfektion (CSF) untersucht. Die Krankengeschichten von unter vier Monate alien Säuglingen, bei denen in der Zeit von 1977 bis 1987 im Krankenhaus Liquorkulturen angelegt worden waren, wurden retrospektiv analysiert: Kinder, bei denen Enteroviren im Liquor nachgewiesen wurden (Gruppe 1), wurden mit Kindern verglichen, bei denen Enteroviren nur in anderem Material gefunden wurden (Gruppe 2). Beurteilungen des prognostischen Wertes (PV) haben egeben, daß keine einzelne oder kombinierte Kultur von nicht‐Liquor Material mit Sicherheit den Nachweis von Enteroviren im Liquor voraussagen konnte. Diese Ergebnisse zeigen, daß für die Diagnose einer Meningitis durch Enteroviren bei Säuglingen eine Liquorkultur erforderlich ist. RESUMEN Valor de cultivos virales, realizados en puntos no LCR, en el diagnóstico de la infección enteroviral del SNC en lactantes Los criterios de laboratorio usados para el diagnóstico de presunción de una meningitis enteroviral fueron evaluados como predictores de la infección del LCT. Se analizaron retrospectivamente las historias de los lactantes de menos de cuatro meses de edad ingresados en el hospital des...

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“…Studies of aseptic meningitis in children are usually concerned with the outbreak of specific enteroviral infections (143,176,209,228,254,256,286,344). There are few recent studies which have reported the entire spectrum of causes of aseptic meningitis in children ( Table 7).…”

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confidence: 99%

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1993

Acta Paediatrica

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Echovirus Type 7 Meningitis in Young Children

Cited by 10 publications

References 14 publications

Echovirus 6 associated to aseptic meningitis outbreak, in São Joaquim da Barra, São Paulo, Brazil

Echovirus 6 associated to aseptic meningitis outbreak, in São Joaquim da Barra, São Paulo, Brazil

Suspect Value of Non‐csf Viral Cultures in the Diagnosis of Enteroviral CNS Infection in Young Infants

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