2017
DOI: 10.1590/s1677-5538.ibju.2016.0002
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ECLAMC Study: prevalence patterns of hypospadias in South America: multi-national analysis over a 24-year period

Abstract: Objective To evaluate prevalence trends of hypospadias in South-America it is essential to perform multicenter and multinational studies with the same methodology. Herein we present systematic data as part of an international multicenter initiative evaluating congenital malformations in South America over a 24-year period.Materials and Methods A nested case-control study was conducted using the Latin American Collaborative Study of Congenital Malformations (ECLAMC), between January 1989 and December 2012. Case… Show more

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Cited by 19 publications
(13 citation statements)
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References 18 publications
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“…As the birth prevalence of hypospadias increases across the world [4,5,6,7,8,9,10], research into the association between pollutant exposure and hypospadias has defined a critical exposure period as the early first trimester of pregnancy [11]. Pollutants which interfere with MET during genitourinary development or hormonal cascades may play a role in hypospadias etiology.…”
Section: Introductionmentioning
confidence: 99%
“…As the birth prevalence of hypospadias increases across the world [4,5,6,7,8,9,10], research into the association between pollutant exposure and hypospadias has defined a critical exposure period as the early first trimester of pregnancy [11]. Pollutants which interfere with MET during genitourinary development or hormonal cascades may play a role in hypospadias etiology.…”
Section: Introductionmentioning
confidence: 99%
“…The Colombian programs have reviewed the descriptive epidemiology of congenital heart defects (Tassinari et al 2018), hypospadias (Fernández et al 2017;Baltaxe and Zarante 2006), and BD in general (Zarante et al 2010). The Bogotá program described the sonographic detection of congenital heart defects has been described in the city of Bogotá (García et al 2014).…”
Section: Discussionmentioning
confidence: 99%
“…En 2017, el equipo de Zarante publicó un análisis de los patrones de prevalencia de hipospadias en Sudamérica, y mostró una prevalencia de 1,13 de cada 1000 partos y un incremento total del 3,3% a lo largo de las últimas dos décadas (45). Paulozzi informa que la primera y segunda anomalía congénita más frecuente en Estados Unidos en el recién nacido varón sería la criptorquidia y la hipospadias, respectivamente (46).…”
Section: Causas Del Escaso Desarrollo Del Estudio De Las Anomalías Geunclassified