Eclipta prostrata (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities

Timalsina, Deepak; Devkota, Hari Prasad

doi:10.3390/biom11111738

Cited by 58 publications

(40 citation statements)

References 70 publications

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“…In this study, we are interested in Eclipta prostrata L. (E. prostrata L.) due to their pharmacological properties. E. prostrata L., commonly known as False daisy, Ink plant, Bhringraj, Bhumiraj, Aali jhar, or Nash jhar, is a herbaceous plant that belongs to the family Asteraceae [4]. It is a weed that grows in moist places such as rivers, marshes or the edge of rice fields [4,5].…”

Section: Introductionmentioning

confidence: 99%

“…It is a weed that grows in moist places such as rivers, marshes or the edge of rice fields [4,5]. It is found in many parts of the world, including Thailand, China, India, Nepal, and Brazil [4]. It has been long used in several diseases such as coronary heart disease, diabetes, gastrointestinal diseases, respiratory diseases, skin diseases, and wounds [5].…”

Section: Introductionmentioning

confidence: 99%

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Development of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin

Hasatsri¹,

Suthi²,

Siriwut³

et al. 2023

Preprint

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Developing novel wound dressings containing medicinal plant extracts can have several potential benefits, including improving the therapeutic value of the dressings and reducing the cost of producing wound dressings. In this study, we prepared foam dressing containing Eclipta prostrata leaf extract and gelatin (Eclipta prostrata dressing). Chemical composition was verified using Fourier transform infrared spectroscopy (FTIR), and pore structure was obtained by scanning electron microscopy (SEM). The physical properties, including absorption and dehydration properties, were also evaluated. The chemical properties were measured to determine the pH environment after being submerged with Eclipta prostrata dressings. The results revealed that the Eclipta prostrata dressing had a pore structure with an appropriate pore size (313.25 ± 76.51 µm and 383.26 ± 64.45 µm for the Eclipta prostrata A and Eclipta prostrata B dressings, respectively). The Eclipta prostrata B dressing was more consistent porosity, resulting in a higher absorption capacity and faster dehydration rate. According to physical properties, the Eclipta prostrata B dressing is best used on low-exuding wounds. Furthermore, the Eclipta prostrata A and B dressings make a slightly acidic environment. Therefore, our foam dressing will not interfere wound healing process.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Development of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin

Hasatsri¹,

Suthi²,

Siriwut³

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Taproot is present. Herbaceous stem mostly branched; nodes are mostly brown or dark in color (Gurrapu & Mamidala, 2017;Mithun et al, 2011;Timalsina & Devkota, 2021;Udayashankar et al, 2019).The entire plant of E. alba and its seeds have incredible therapeutic worth. The chronic and tainted injuries show signs of improvement with use of its glue.…”

Section: Introductionmentioning

confidence: 99%

Light and scanning electron microscopic comparative studies of geminivirus infected and healthy Eclipta alba (L.)

Sonia

Shaheen

Khalid

et al. 2022

Microscopy Res & Technique

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Eclipta alba (L.) is a valuable medicinal plant. However, its medicinal efficacy can be affected by geminivirus infection. Therefore, identification of healthy specimen is essential before to use as medicine. The present study provided the taxonomic characterization of geminivirus infected and healthy E. alba plant by studying apparent morphology and microscopic features through light and scanning electron microscopy. Before taxonomic characterization infected and healthy specimens were separated through molecular detection of geminivirus. Results of morphological studies reported that geminivirus infected E. alba plant showed systematic symptoms of infection like stunted growth, distortion and chlorosis of leaves, decrease in size of root, shoot and fruit, and so forth in comparison to healthy specimen. Anatomical findings reported that in both plants anomocytic and anisocytic types of stomata with multicellular warty trichomes were present. However, variations were observed in quantitative measures such as size of trichomes, epidermal, subsidiary and guard cells. Palynological observations identifies that both plants possessed tricolporate type of pollen but variation was mainly observed in size and shape of pollen, thickness of exine and intine, P/E ratio, pore size, interspecific difference, size of colpi, and pollen ornamentation. Overall this study concluded that both healthy and infected E. alba do not reported much variations in qualitative taxonomic features, but can be differentiated in terms of quantitative taxonomic evidences. Future studies are recommended for pharmacological analysis of both healthy and virus infected plants. Research HighlightsEclipta alba has incredible therapeutic worth, but due to geminivirus infection the plant is affecting badly. Hence, the present studies give a comprehensive taxonomic report on the geminivirus infected and healthy plant species.

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“…R.Br. and E. prostrata (L.) L. plants, besides having flavonoid content, they have also been used by the local community as an empirical treatment Since 2002 https://oamjms.eu/index.php/mjms/index for hypertension [17], [18]. Therefore, this study was conducted to assess the ability of the four plants and their potential in inhibiting ACE activity and discover a possible new ACE inhibition activity using an in vitro ACE inhibition assay.…”

Section: Introductionmentioning

confidence: 99%

Potential Use of Some Indonesian Plants to Inhibits Angiotensin-converting Enzyme In Vitro

Sandhiutami

Dewi

Rahma

et al. 2022

Open Access Maced J Med Sci

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BACKGROUND: Some Indonesian plants, such as Vaccinium varingiaefolium Miq., Plectranthus scutellarioides (L.) R.Br., Syzygium myrtifolium Walp., and Eclipta prostrata (L.) L., are rich of flavonoid and anthocyanin. Flavonoid, flavan-3-ol, quercetin, anthocyanin, and tannin compounds can reduce systemic vascular resistance because they cause vasodilation and are thought to be able to influence the function of angiotensin-converting enzyme (ACE) and inhibit ACE activity, which plays an important role in the process of hypertension. AIM: This study aims to determine the potential of some Indonesian plants to inhibit ACE activity. METHODS: Testing of ACE inhibitory activity is carried out by the hippuric acid compounds formed as a result of the reaction between the substrate and the enzyme, then measured spectrophotometrically. The inhibitory and IC50 values of each test sample were compared with the positive control of Captopril. RESULTS: The four plant extracts contained secondary metabolites, such as flavonoids, tannins, saponins, quinones, steroids, triterpenoids, and essential oils. Ethanol extract of V. varingiaefolium Miq., P. scutellarioides (L.) R.Br., S. myrtifolium Walp., and E. prostrata (L.) L. each had an IC50 value of ACE inhibition activity of 131.4 ppm, 206. 7 ppm, 151.2 ppm, and 196.0 ppm. The IC50 value of the Captopril with inhibition of ACE activity is 11.1 ppm. CONCLUSION: This study shows that some Indonesian plants have the activity to inhibit the ACE and potential antihypertensive drug candidates with ACE inhibitory activity.

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Eclipta prostrata (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities

Cited by 58 publications

References 70 publications

Development of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin

Development of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin

Light and scanning electron microscopic comparative studies of geminivirus infected and healthy Eclipta alba (L.)

Potential Use of Some Indonesian Plants to Inhibits Angiotensin-converting Enzyme In Vitro

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