Eco-Friendly Greener Synthesis of Nanoparticles

Bhardwaj, Brahamdutt; Singh, Pritam; Kumar, Arun; Kumar, Sandeep; Budhwar, Vikas

doi:10.34172/apb.2020.067

Cited by 124 publications

(31 citation statements)

References 85 publications

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“…Studies of copper oxideand other metals and metal oxides (silver, gold, palladium selenium, zinc oxide, and titanium dioxide)in the form of nanoparticles have focused on their antifungal efficacy. − In particular, the role played by the surface composition of the nanoparticles in their antimicrobial activity has been studied . Al-Awady et al, for example, developed polyelectrolyte-coated titania NPs with up to four layers of polyelectrolytes of alternating charge.…”

Section: Introductionmentioning

confidence: 99%

Red Microalgal Sulfated Polysaccharide–Cu₂O Complexes: Characterization and Bioactivity

Yehuda

Shalish

Kushmaro

et al. 2021

ACS Appl. Mater. Interfaces

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The anion-exchange capacity of the cell-wall sulfated polysaccharide of the red microalga Porphyridium sp. can be exploited for the complexation of metal ions (e.g., Cu, Zn, Ag) to produce novel materials with new bioactivities. In this study, we investigated this algal polysaccharide as a platform for the incorporation of copper as Cu2O. Chemical and rheological characterization of the Cu2O–polysaccharide complex showed that the copper is covalently bound to the polysaccharide and that the complex exhibits higher viscosity and conductivity than the native polysaccharide. Examination of the complex’s inhibitory activity against the bacteria Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, and Bacillus subtilis and the fungus Candida albicans revealed a relatively high antimicrobial activity, especially against C. albicans (92% growth inhibition) as compared to the polysaccharide and to Cu2O alone. The antibiofilm activity was also found against P. aeruginosa PA14 and C. albicans biofilms. An atomic force microscopy examination of the surface morphology of the complex revealed needle-like structures (spikes), approximately 10 nm thick, protruding from the complex surface to a maximum height of 1000 nm, at a density of about 5000/μm2, which were not detected in the native polysaccharide. It seems that the spikes on the surface of the Cu2O–polysaccharide complex are responsible for the antimicrobial activities of the complex, that is, for disruption of microbial membrane permeability, leading to cell death. The study thus indicates that the superior qualities of the novel material formed by complexion of Cu2O to the polysaccharide should be studied further for various biotechnological applications.

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Section: Introductionmentioning

confidence: 99%

Red Microalgal Sulfated Polysaccharide–Cu₂O Complexes: Characterization and Bioactivity

Yehuda

Shalish

Kushmaro

et al. 2021

ACS Appl. Mater. Interfaces

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“…Plant-based extracts and microorganism cultures have been employed all around the world to make NPs that are more environmentally friendly. Microbes are a good choice for NP synthesis because of their rapid growth rate, low cost of cultivation, and ability to survive in a variety of environmental variables such as temperature, pressure, and pH [23][24][25][26][27][28][29][30][31]. Fungi are one of the most significant microbe groups, since they are utilized in a variety of applications including bioprocessing, dyes removal, enzyme synthesis, food items, and nanotechnology [32][33][34].…”

Section: Introductionmentioning

confidence: 99%

Environmental Impacts of Ecofriendly Iron Oxide Nanoparticles on Dyes Removal and Antibacterial Activity

Hammad

Salem

Mohamed

et al. 2022

Appl Biochem Biotechnol

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Biosynthesized nanoparticles have a promising future since they are a more environmentally friendly, cost-effective, repeatable, and energy-efficient technique than physical or chemical synthesis. In this work, Purpureocillium lilacinum was used to synthesize iron oxide nanoparticles (Fe2O3-NPs). Characterization of mycosynthesized Fe2O3-NPs was done by using UV–vis spectroscopy, transmission electron microscope (TEM), dynamic light scattering (DLS), and X-ray diffraction (XRD) analysis. UV–vis gave characteristic surface plasmon resonance (SPR) peak for Fe2O3-NPs at 380 nm. TEM image reveals that the morphology of biosynthesized Fe2O3-NPs was hexagonal, and their size range between 13.13 and 24.93 nm. From the XRD analysis, it was confirmed the crystalline nature of Fe2O3 with average size 57.9 nm. Further comparative study of photocatalytic decolorization of navy blue (NB) and safranin (S) using Fe2O3-NPs was done. Fe2O3-NPs exhibited potential catalytic activity with a reduction of 49.3% and 66% of navy blue and safranin, respectively. Further, the antimicrobial activity of Fe2O3-NPs was analyzed against pathogenic bacteria (Pseudomonas aeruginosa, Escherichia coli, Bacillus subtilis, and Staphylococcus aureus). The Fe2O3-NPs were clearly more effective on gram-positive bacteria (S. aureus and B. subtilis) than gram-negative bacteria (E. coli and P. aeruginosa). Thus, the mycosynthesized Fe2O3-NPs exhibited an ecofriendly, sustainable, and effective route for decolorization of navy blue and safranin dyes and antibacterial activity.

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“…In general, conventional synthetic methods used to obtain NPs require the use of toxic and hazardous agents [31][32][33]. To overcome this limitation, recent efforts have been made to replace such procedures with eco-friendly protocols [34][35][36], based on the use of plant or microorganism extracts as sources of reducing and capping agents [34,37]. The synthesis of metallic NPs mediated by plants can be obtained employing extracellular and intracellular routes [38]; moreover, phytochemicals previously isolated from plants are used to obtain NPs [39,40].…”

Section: Introductionmentioning

confidence: 99%

Green Silver Nanoparticles Promote Inflammation Shutdown in Human Leukemic Monocytes

et al. 2022

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The use of silver nanoparticles (Ag NPs) in the biomedical field deserves a mindful analysis of the possible inflammatory response which could limit their use in the clinic. Despite the anti-cancer properties of Ag NPs having been widely demonstrated, there are still few studies concerning their involvement in the activation of specific inflammatory pathways. The inflammatory outcome depends on the synthetic route used in the NPs production, in which toxic reagents are employed. In this work, we compared two types of Ag NPs, obtained by two different chemical routes: conventional synthesis using sodium citrate and a green protocol based on leaf extracts as a source of reduction and capping agents. A careful physicochemical characterization was carried out showing spherical and stable Ag NPs with an average size between 20 nm and 35 nm for conventional and green Ag NPs respectively. Then, we evaluated their ability to induce the activation of inflammation in Human Leukemic Monocytes (THP-1) differentiated into M0 macrophages using 1 µM and 2 µM NPs concentrations (corresponded to 0.1 µg/mL and 0.2 µg/mL respectively) and two-time points (24 h and 48 h). Our results showed a clear difference in Nuclear Factor κB (NF-κb) activation, Interleukins 6–8 (IL-6, IL-8) secretion, Tumor Necrosis Factor-α (TNF-α) and Cyclooxygenase-2 (COX-2) expression exerted by the two kinds of Ag NPs. Green Ag NPs were definitely tolerated by macrophages compared to conventional Ag NPs which induced the activation of all the factors mentioned above. Subsequently, the exposure of breast cancer cell line (MCF-7) to the green Ag NPs showed that they exhibited antitumor activity like the conventional ones, but surprisingly, using the MCF-10A line (not tumoral breast cells) the green Ag NPs did not cause a significant decrease in cell viability.

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Eco-Friendly Greener Synthesis of Nanoparticles

Cited by 124 publications

References 85 publications

Red Microalgal Sulfated Polysaccharide–Cu₂O Complexes: Characterization and Bioactivity

Red Microalgal Sulfated Polysaccharide–Cu₂O Complexes: Characterization and Bioactivity

Environmental Impacts of Ecofriendly Iron Oxide Nanoparticles on Dyes Removal and Antibacterial Activity

Green Silver Nanoparticles Promote Inflammation Shutdown in Human Leukemic Monocytes

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Eco-Friendly Greener Synthesis of Nanoparticles

Cited by 124 publications

References 85 publications

Red Microalgal Sulfated Polysaccharide–Cu2O Complexes: Characterization and Bioactivity

Red Microalgal Sulfated Polysaccharide–Cu2O Complexes: Characterization and Bioactivity

Environmental Impacts of Ecofriendly Iron Oxide Nanoparticles on Dyes Removal and Antibacterial Activity

Green Silver Nanoparticles Promote Inflammation Shutdown in Human Leukemic Monocytes

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Product

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Red Microalgal Sulfated Polysaccharide–Cu₂O Complexes: Characterization and Bioactivity

Red Microalgal Sulfated Polysaccharide–Cu₂O Complexes: Characterization and Bioactivity