Eco-Friendly Synthesis of Biocompatible Pectin Stabilized Graphene Nanosheets Hydrogel and Their Application for the Simultaneous Electrochemical Determination of Dopamine and Paracetamol in Real Samples

Abstract

The development of novel and simple active sensing materials is still interested to fabricate a new and improved sensing devices for many industrial, medical and environmental applications. In this work, we have synthesized a new type of pectin (PT) and reduced graphene oxide (RGO) hydrogels (PT/RGO) by using simple sonochemical methods and further used as an active sensing material for simultaneous electrochemical detection of dopamine (DA) and paracetamol (AC). In general, PT and RGO have substantial electrocatalytic activity due to the presence of active functional groups. Herein, the successful formation of PT wrapped RGO was studied by using various analytical techniques. Subsequently, the electrochemical performance of PT/RGO modified glassy carbon electrode (GCE) toward the detection of DA and AC were systematically examined by using cyclic voltammetry (CV) and linear sweep voltammetry (LSV) techniques. As the results, PT/RGO/GCE exhibits the excellent electrochemical activity with a low detection limit (LOD) of 1.5 nM and 1.8 nM, for DA and AC respectively. Especially, the possible mechanism behind the proposed sensor (PT/RGO/GCE) toward detection of DA and AC was clearly scrutinized. In addition, the observed excellent stability, and selectivity of PT/RGO/GCE greater support for the real time detection of DA and AC in human serum and pharmaceutical samples. Thus, the proposed PT/RGO is believed as an exclusive active sensing material with desired properties for future electrochemical sensor applications.

A Facile Fabrication of Poly‐ethionine Film on Glassy Carbon Electrode for Simultaneous and Sensitive Detection of Dopamine and Paracetamol

“…Similarly for PA, the linear regression equation for oxidation peak currents and reduction peak currents were I pa (μA) = 0.0755υ + 14.153 with correlation coefficient of 0.982 and I pc (μA) = À 0.034υ-8.64 with correlation coefficient of 0.980, respectively. These studies confirmed that the current produced by the electro-chemical redox processes of DA and PA at Poly-ET/GCE was surface controlled one [33,34].…”

Praseodymium Vanadate-Decorated Sulfur-Doped Carbon Nitride Hybrid Nanocomposite: The Role of a Synergistic Electrocatalyst for the Detection of Metronidazole

“…For these reasons, the identification of MTZ in water and soil environments is of importance to researchers. Until now, many approaches have been reported for analysis of MTZ, such as fluorescence techniques, gas chromatography, ion mobility spectrometry, polarography detection, high-performance liquid chromatography, flame ionization detection, mass spectrometry, and UV spectrophotometry. − However, the aforementioned methods are restrictive in being time-consuming, costly, limited in selectivity, and complex. Conversely, electrochemical techniques are a superior choice because of the ease of onsite methodologies, the possibility of miniaturization, low expense, amenable monitoring, sensitivity, portability, and speed which have attracted considerable attention. − …”

Electro-Oxidation and Simultaneous Determination of Indole-3-Acetic Acid and Salicylic Acid on Graphene Hydrogel Modified Electrode

“…Three-dimensional (3D) graphene materials which can be assembled by graphene nanosheets, have improved physical and electrochemical properties when compared to graphene nanosheets [24][25][26]. In recent years, they have gained great attention because of their high specific surface area, good electron mobility, porous, and 3D-networked structure [27][28][29]. Graphene hydrogel (GH) is a 3D graphene material that can be prepared easily by hydrothermal reduction [30][31][32] and chemical reduction [33,34].…”