An electrochemical sensor based on graphene oxide modified glassy carbon electrode for the determination of anti-cancer drug flutamide.

Electrochemical detection of 8-OHdG biomarker using Dy2O3@RGO/SPCE.

The development of novel and simple active sensing materials is still interested to fabricate a new and improved sensing devices for many industrial, medical and environmental applications. In this work, we have synthesized a new type of pectin (PT) and reduced graphene oxide (RGO) hydrogels (PT/RGO) by using simple sonochemical methods and further used as an active sensing material for simultaneous electrochemical detection of dopamine (DA) and paracetamol (AC). In general, PT and RGO have substantial electrocatalytic activity due to the presence of active functional groups. Herein, the successful formation of PT wrapped RGO was studied by using various analytical techniques. Subsequently, the electrochemical performance of PT/RGO modified glassy carbon electrode (GCE) toward the detection of DA and AC were systematically examined by using cyclic voltammetry (CV) and linear sweep voltammetry (LSV) techniques. As the results, PT/RGO/GCE exhibits the excellent electrochemical activity with a low detection limit (LOD) of 1.5 nM and 1.8 nM, for DA and AC respectively. Especially, the possible mechanism behind the proposed sensor (PT/RGO/GCE) toward detection of DA and AC was clearly scrutinized. In addition, the observed excellent stability, and selectivity of PT/RGO/GCE greater support for the real time detection of DA and AC in human serum and pharmaceutical samples. Thus, the proposed PT/RGO is believed as an exclusive active sensing material with desired properties for future electrochemical sensor applications.

Present strategy reports a simple electrochemical sensor for highly sensitive, selective detection of carbamazepine based on the graphene oxide and graphitic carbon nitride composite film modified electrode. The GO/g-C 3 N 4 composite film exhibit incredible electrocatalytic activity in terms of minimized over potential (0.1 V) associated with enhanced anodic current with 4 fold higher than that of control electrode. In addition, the developed sensor yields a very lower detection limit (10.5 nM) with good sensitivity (1.727 μA μM −1 cm −2 ). Furthermore, the developed assay was employed in the determination of CBZ in human urine samples and pharmaceutical samples. Analytical results are reliable, suggested that the proposed sensor can be used for the determination of CBZ in biological and pharmaceutical samples.

This review expresses recent trends in electrocatalysts towards hydrogen production and water oxidation. The recent and future trends with different strategies for the development of electrocatalysts for fuel cells are highlighted.