An Amperometric Sensor for Low Level Detection of Antidepressant Drug Carbamazepine Based on Graphene Oxide-g-C₃N₄Composite Film Modified Electrode

Abstract

Present strategy reports a simple electrochemical sensor for highly sensitive, selective detection of carbamazepine based on the graphene oxide and graphitic carbon nitride composite film modified electrode. The GO/g-C 3 N 4 composite film exhibit incredible electrocatalytic activity in terms of minimized over potential (0.1 V) associated with enhanced anodic current with 4 fold higher than that of control electrode. In addition, the developed sensor yields a very lower detection limit (10.5 nM) with good sensitivity (1.727 μA μM −1 cm −2 ). Furthermore, the developed assay was employed in the determination of CBZ in human urine samples and pharmaceutical samples. Analytical results are reliable, suggested that the proposed sensor can be used for the determination of CBZ in biological and pharmaceutical samples.

Host–Guest Recognition on 2D Graphitic Carbon Nitride for Nanosensing

“…[169] The g-C 3 N 4 H + nanosheets were further doped with cylindrical spongy polypyrrole (CSPPy-g-C 3 carbamazepine. [170] The sensor shows a low LOD (10.5 nM) and good sensitivity (1.727 µA•mM -1 •cm -2 ). Furthermore, the as-prepared assay was employed for the detection of CBZ in human urine and pharmaceutical samples (Figure 12i-l).…”

“…[168] Copyright 2016, Elsevier B.V.; (i-l) Reproduced with permission. [170] Copyright 2018, Wiley-VCH Verlag GmbH & Co. KgaA.…”

Two-Dimensional Metallic NiSe2 Nanoclusters–Based Low-Cost, Flexible, Amperometric Sensor for Detection of Neurological Drug Carbamazepine in Human Sweat Samples

“…Table 2 summarizes the performance of the as-fabricated NiSe 2 on PI-based sensor with the previous reports on state-of-the-art 2D materials-based sensors for detection of CBZ. Nanomaterials-based composites such as rGO -SWNT (Unnikrishnan et al, 2012), GO -C 3 N 4 (Balasubramanian et al, 2018), and graphene-AuNPs (Lavanya et al, 2016) have been used as electrodes for CBZ detection. However, the synthesis procedure involved two steps, namely, (i) Hummers method for graphene-based materials, (ii) chemical synthesis methods such as polymerization and precipitation for SWNT or g-C 3 N 4 .…”

Interfacial TiN bonding of a g-C3N4/TiH1.92 type-II heterojunction photocatalyst significantly enhanced photocatalytic hydrogen evolution from water splitting

“…31 Meanwhile, the strong absorption peaks at 1230-1634 cm −1 are assigned to typical stretching modes of aromatic C-N and CN heterocyclic groups. 32 The broad bands ranging from 2900 cm −1 to 3600 cm −1 are attributed to the stretching vibration of C-NH 2 and C-NH bonds that exist as an uncondensed amino group in the molecular edge of g-C 3 N 4 . 33 From the FTIR spectrum of TiH 1.92 , it can be seen that the peaks located at 1670-1683 cm −1 are assigned to the Ti-H stretching peaks.…”