Economic and clinical benefits of radiofrequency ablation versus hysterectomy in patients suffering from menorrhagia: a retrospective analysis with German health claims data

Kessel, Sebastian; Hucke, J.; Goergen, Christoph; Soeder, Ruediger; Roemer, Thomas

doi:10.1586/17434440.2015.1015988

Cited by 5 publications

(4 citation statements)

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“…Figure 2 shows that 21 studies (60.0%) evaluated health care programs such as disease management programs which were assessed in 8 studies (22.9%) alone [ 21 , 25 – 27 , 37 , 39 , 43 , 49 ]. Evaluations were also performed on pharmaceuticals in 8 studies (22.8%) [ 30 , 35 , 41 , 44 – 48 ] and medical products or procedures in 6 studies (17.1%) [ 2 , 3 , 23 , 24 , 36 , 50 ]. Funding can mainly be ascribed to industry ( n = 15, 42.9%) – generally the involved health insurance fund or product manufacturer – or public sources ( n = 8, 22.9%).…”

Section: Resultsmentioning

confidence: 99%

“…Of the remaining studies, 4 (11.4%) used claims data from several different health insurance funds – 2 of which (5.7%) specified which funds were involved [ 45 , 46 ]. The other two studies (5.7%) referred to a SHI database [ 24 , 36 ]. Finally, two studies (5.7%) did not specify which individual fund supplied the data [ 34 , 37 ].…”

Section: Resultsmentioning

confidence: 99%

“…Generally, the score is estimated by logistic regression – as was the case in 86.6% ( n = 13) of the 15 studies that applied PSM [ 2 , 3 , 22 – 27 , 31 , 34 , 42 , 43 , 49 ]. Two of these studies (13.3%) gave no details on the estimation method [ 36 , 39 ]. Two studies (13.3%) combined PSM with exact matching of individuals in one or more characteristic (e.g.…”

Section: Resultsmentioning

confidence: 99%

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Health economic evaluations based on routine data in Germany: a systematic review

Gansen

2018

BMC Health Serv Res

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BackgroundImproved data access and funding for health services research have promoted the application of routine data to measure costs and effects of interventions within the German health care system. Following the trend towards real world evidence, this review aims to evaluate the status and quality of health economic evaluations based on routine data in Germany.MethodsTo identify relevant economic evaluations, a systematic literature search in the databases PubMed and EMBASE was complemented by a manual search. The included studies had to be full economic evaluations using German routine data to measure either costs, effects, or both. Study characteristics were assessed with a structured template. Additionally, the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) were used to measure quality of reporting.ResultsIn total, 912 records were identified and 35 studies were included in the further analysis. The majority of these studies was published in the past 5 years (n = 27, 77.1%) and used insurance claims data as a source of routine data (n = 30, 85.7%). The most common method used for handling selection bias was propensity score matching. With regard to the reporting quality, 42.9% (n = 15) of the studies satisfied at least 80% of the criteria on the CHEERS checklist.ConclusionsThis review confirms that routine data has become an increasingly common data source for health economic evaluations in Germany. While most studies addressed the application of routine data, this analysis reveals deficits in considering methodological particularities and in reporting quality of economic evaluations based on routine data. Nevertheless, this review demonstrates the overall potential of routine data for economic evaluations.Electronic supplementary materialThe online version of this article (10.1186/s12913-018-3080-3) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Health economic evaluations based on routine data in Germany: a systematic review

Gansen

2018

BMC Health Serv Res

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“…This study was performed following an analysis that reported the clinical and economic benefits of RFA compared with hysterectomy in women with menorrhagia; Kessel et al reported a total savings of €1,771 within 2 years after the first treatment when treating menorrhagia with RFA instead of hysterectomy. 21 …”

Section: Discussionmentioning

confidence: 99%

Economic and clinical benefits of endometrial radiofrequency ablation compared with other ablation techniques in women with menorrhagia: a retrospective analysis with German health claims data

Bischoff-Everding

Soeder²,

Neukirch³

2016

IJWH

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ObjectiveTo evaluate the economic and clinical benefits of endometrial radiofrequency ablation (RFA) compared with other ablation techniques for the treatment of menorrhagia.MethodsUsing German health claims data, women meeting defined inclusion criteria for the intervention group (RFA) were selected. A comparable control group (other endometrial ablations) was established using propensity score matching. These two groups were compared during the quarter of treatment (QoT) and a follow-up of 2 years for the following outcomes: costs during QoT and during follow-up, repeated menorrhagia diagnoses during follow-up and necessary retreatments during follow-up.ResultsAfter performing propensity score matching, 50 cases could be allocated to the intervention group, while 38 were identified as control cases. Patients in the RFA group had 5% fewer repeat menorrhagia diagnoses (40% vs 45%; not significant) and 5% fewer treatments associated with recurrent menorrhagia (6% vs 11%; not significant) than cases in the control group. During the QoT, the RFA group incurred €578 additional costs (€2,068 vs €1,490; ns). However, during follow-up, the control group incurred €1,254 additional costs (€4,561 vs €5,815; ns), with medication, outpatient physician consultations, and hospitals costs being the main cost drivers. However, none of the results were statistically significant.ConclusionAlthough RFA was more cost-intensive in the QoT compared with other endometrial ablation techniques, an average total savings of €676 was generated during the follow-up period. While having evidence that RFA is clinically equivalent to other endometrial ablation procedures, we generated indications that RFA is non-inferior and favorable with regard to economic outcomes.

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Selektivverträge als Instrument des Market Access

Makowski

2019

Market Access in Der Medizintechnik

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Economic and clinical benefits of radiofrequency ablation versus hysterectomy in patients suffering from menorrhagia: a retrospective analysis with German health claims data

Abstract: RFA should more often be considered a relevant treatment option both from an economic and a medical point of view.

Cited by 5 publications

References 15 publications

Health economic evaluations based on routine data in Germany: a systematic review

Health economic evaluations based on routine data in Germany: a systematic review

Economic and clinical benefits of endometrial radiofrequency ablation compared with other ablation techniques in women with menorrhagia: a retrospective analysis with German health claims data

Selektivverträge als Instrument des Market Access

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Economic and clinical benefits of radiofrequency ablation versus hysterectomy in patients suffering from menorrhagia: a retrospective analysis with German health claims data

Abstract: RFA should more often be considered a relevant treatment option both from an economic and a medical point of view.

Cited by 5 publications

References 15 publications

Health economic evaluations based on routine data in Germany: a systematic review

Health economic evaluations based on routine data in Germany: a systematic review

Economic and clinical benefits of endometrial radiofrequency ablation compared with other ablation techniques in women with menorrhagia: a&nbsp;retrospective analysis with German health claims data

Selektivverträge als Instrument des Market Access

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Economic and clinical benefits of endometrial radiofrequency ablation compared with other ablation techniques in women with menorrhagia: a retrospective analysis with German health claims data