The environmental impact of the energy sector and the security and economics of energy supply and utilization have been raising increasing concerns, stimulating the search for innovative solutions for a sustainable use of resources. This article provides an overview of published research in this area, with a focus on papers contributed in special issues of leading journals dedicated to the series of Conferences on Sustainable Development of Energy, Water and Environment Systems (SDEWES), including the articles in the current special issue. Based on this review, research trends are identified and achievements supporting the energy transition are highlighted. The studies that focused on regional or urban energy planning have aimed at (a) increasing penetration of renewable energy sources, (b) optimizing the mix of centralized and distributed technologies (c) introducing additional flexibility in the power sector and d) identifying solutions for sustainable heating. Conversely, researches focused on individual plants or users have targeted the development of technologies for efficient energy use in industry and buildings, with emphasis on multigeneration and waste heat utilisation. The analysis highlights that future scenarios based on sustainable energy systems are viable, although their implementation will require further efforts by researchers and investors and active involvement of consumers.