Economic burden of recurrent venous thromboembolism: Analysis from a U.S. hospital perspective

Casciano, Julian; Dotiwala, Zenobia; Kemp, Robert; Li, Chenghui; Cai, Jennifer; Preblick, Ronald

doi:10.2146/ajhp140204

Cited by 15 publications

(10 citation statements)

References 30 publications

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“…19 As VTE disproportionately affects the older population, it is anticipated that incidence of VTE, and thus risk of recurrence, will increase with an aging population. 20 Multiple VTE events are associated with increased risk of chronic complications, including pulmonary hypertension and postthrombotic syndrome, 21 with burden and costs extending beyond the 1-year time horizon of this study. Thus, it is plausible that recurrent VTE is associated with additional costs not captured in this study, resulting in an underestimation of total cost of VTE.…”

Section: Discussionmentioning

confidence: 96%

Health-care Cost Impact of Continued Anticoagulation With Rivaroxaban vs Aspirin for Prevention of Recurrent Symptomatic VTE in the EINSTEIN-CHOICE Trial Population

Wells

Prins

Beyer‐Westendorf

et al. 2018

Chest

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Section: Discussionmentioning

confidence: 96%

Health-care Cost Impact of Continued Anticoagulation With Rivaroxaban vs Aspirin for Prevention of Recurrent Symptomatic VTE in the EINSTEIN-CHOICE Trial Population

Wells

Prins

Beyer‐Westendorf

et al. 2018

Chest

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“…Nieco niższe ryzyko stwarzają zabiegi artroskopowe stawu kolanowego oraz unieruchomienie trwające więcej niż trzy dni. [1] [2] [5]. W przypadku operacji ortopedycznych kończyny górnej powikłania zakrzepowo-zatorowe występują rzadziej.…”

Section: Czynniki Determinujące Ryzyko Wystąpienia Incydentów Zakrzep...unclassified

Prophylaxis of thromboembolic complications in patients undergoing orthopedic surgery

Małek

Wysokińska

Żyga³

et al. 2022

J Educ Health Sport

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Venous thromboembolism is undoubtedly one of the frequent and dangerous complications after orthopedic surgery. If not detected in time, it can lead to very serious consequences concerning the patient's health and life. Therefore, it is crucial to know the risk factors for thromboembolic incidents. Among these factors, we can distinguish those related to the patient, his or her health status, lifestyle and factors that depend on the type of orthopedic intervention performed. Each patient should undergo an individual assessment of risk factors before undergoing surgery. Undoubtedly, an important role is played by observing the patient to detect early and late symptoms, as well as appropriate care in the postoperative period to reduce the risk of thromboembolic incidents. It is important to catch the disease at an early stage and undertake appropriate diagnostics to exclude or confirm the disease. The risk of venous thromboembolism can be lowered by using thromboprophylaxis. Various forms of prevention are available, which include various methods and means of prevention. An appropriate approach to the problem of the occurrence of this type of complication after orthopedic surgery affects not only the results of the treatment of orthopedic conditions, but also the overall health and functioning of the patient and his prognosis.

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“…Furthermore, VTE is associated with significant costs for patients and the health care system. Patients with VTE have more hospital admissions (1.07 vs 0.15), emergency room visits (0.31 vs 0.05), and greater total cost ($28,353 vs $17,712) compared to patients without VTE [12]. Therefore, there is a need to improve perioperative management and reduce the incidence of VTE.…”

Section: Introductionmentioning

confidence: 99%

Perioperative venous thromboembolism prophylaxis in prostate cancer surgery

et al. 2019

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Purpose: To describe a patient and procedure specific approach to selecting Venous thromboembolism (VTE) prophylaxis for men who undergo radical prostatectomy. Methods: We performed a literature search and narrative review of VTE after radical prostatectomy. We describe the current paradigm of perioperative thromboprophylaxis and underlying rationale. Relevant findings from the European Association of Urology thromboprophylaxis guidelines are interpreted and summarized. Results: The use of extended post-operative thromboprophylaxis for patients who undergo radical prostatectomy is appropriate when the risk of symptomatic VTE outweighs the risk of major bleeding. Patient and procedure factors impact VTE risk. Patient risk can be stratified as low, moderate or high based on 4 factors; age >75, BMI>35, VTE in a first degree relative, and personal history of VTE. Procedure risk of VTE and bleeding can be stratified by modality of surgery (open, laparoscopic, robotic) and extent of pelvic lymphadenectomy. Using these factors, patients at the lowest risk for VTE will have an expected incidence of VTE of 0.4-0.8% and those at highest risk from 1.5-15.7%. Incidence of major bleeding ranges from 0.4-1.4%. These ranges emphasize the need to consider the net benefit for each specific patient. Use of mechanical prophylaxis is supported by weaker evidence but has fewer harms and is likely reasonable for most patients Conclusion: Many patients who undergo radical prostatectomy will benefit from extended postoperative thromboprophylaxis. Risk of thrombosis is likely higher with open approach and extended lymph node dissection. The net benefit of treatment should be considered using patient-and procedure-specific criteria. When the net benefit is negligible or possibly harmful no pharmacological thromboprophylaxis should be used.

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Economic burden of recurrent venous thromboembolism: Analysis from a U.S. hospital perspective

Abstract: Patients with recurrent VTE used more hospital resources than those without recurrent VTE. Readmissions for VTE were significantly longer and more costly than index encounters.

Cited by 15 publications

References 30 publications

Health-care Cost Impact of Continued Anticoagulation With Rivaroxaban vs Aspirin for Prevention of Recurrent Symptomatic VTE in the EINSTEIN-CHOICE Trial Population

Health-care Cost Impact of Continued Anticoagulation With Rivaroxaban vs Aspirin for Prevention of Recurrent Symptomatic VTE in the EINSTEIN-CHOICE Trial Population

Prophylaxis of thromboembolic complications in patients undergoing orthopedic surgery

Perioperative venous thromboembolism prophylaxis in prostate cancer surgery

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