Economic Burden of Urinary Tract Infections From Antibiotic-Resistant Escherichia coli Among Hospitalized Adult Patients in Lebanon: A Prospective Cohort Study

Iskandar, Katia; Rizk, Rana; Matta, Roula; Husni-Samaha, Rola; Sacre, Hala; Raad, Etwal Bou; Dirani, Natalia; Salameh, Pascale; Molinier, Laurent; Roques, Christine; Dimassi, Ahmad; Hallit, Souheil; Abdo, Rachel; Hanna, Pierre Abi; Yared, Yasmina; Matta, Matta; Mostafa, Inas

doi:10.1016/j.vhri.2020.01.006

Cited by 3 publications

(2 citation statements)

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“… 105 Few studies described Anorexia Nervosa and investigated the beneficial effect of physical activity on this eating disorder. 106 , 107 As healthcare improvement measures, some studies estimated the differences in clinical and economic outcomes of antibiotic resistance among hospitalized patients 108 , 109 while another publication highlighted the increase in the prevalence of adverse drug events among Lebanese patients with polypharmacy and shed light on the importance of counseling. 110 Furthermore, contemporary gynecologists have described the positive role of aspirin in in-vitro fertilization (IVF) techniques and success rates 111 while other scientists demonstrated the beneficial effects of Plasma-rich protein on the healing of venous leg ulcers in hospitalized patients.…”

Section: Resultsmentioning

confidence: 99%

Identifying health research in the era of COVID-19: A scoping review

Samah

2023

SAGE Open Medicine

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Background: Health improvements are considered one of the most important fields of research. Since the coronavirus disease 2019 was declared a pandemic, it might have impacted clinical and public health research in various forms. Objectives: The goal of this study is to explore health research approaches in the era of coronavirus disease 2019. Methods: In this scoping review, we reviewed published medical full-text studies and identified potential areas of interest of health research in the era the coronavirus disease 2019 pandemic during the last 3 years within a higher educational setting. A bibliometric analysis was used to compare among published works. Results: Among the 93 studies that met the inclusion criteria, most focused on mental health ( n = 23; 24.7%). Twenty-one publications targeted coronavirus disease 2019 and its consequences on general health. Other studies have described hemato-oncological, cardiovascular, respiratory, and endocrinological diseases. 42 studies were cross-sectional or cohort studies and most of them published in Q1 journals. Almost half of them belonged to the Faculty of Medicine (49.5%) followed by the School of Arts, Sciences, and Psychology (26.9%). Conclusions: Health research has been demonstrated to be important, at all times, especially during crises. Therefore, researchers need to invest more efforts into seeking new medical updates in various health-related fields, regardless of their correlation with coronavirus disease 2019.

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Section: Resultsmentioning

confidence: 99%

Identifying health research in the era of COVID-19: A scoping review

Samah

2023

SAGE Open Medicine

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“…Finally, the rising threat of antibiotic resistance among infection cases in general and UTIs in particular has also led to somber predictions in terms of cost risings. A study from Lebanon shown that patients infected with resistant urobacteria have 29% higher hospitalization costs, not only because the aggravated forms of their conditions, but also because of a longer length of stay in the hospital [ 16 ]. In the USA, the healthcare system may be under even more pressure due to this phenomenon, since it may add USD 2.2 billion annually to the costs with UTI patients, which is roughly the total amount of money spent on the remedy of all UTI cases [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Nanotechnology Involved in Treating Urinary Tract Infections: An Overview

et al. 2023

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Considered as the most frequent contaminations that do not require hospitalization, urinary tract infections (UTIs) are largely known to cause significant personal burdens on patients. Although UTIs overall are highly preventable health issues, the recourse to antibiotics as drug treatments for these infections is a worryingly spread approach that should be addressed and gradually overcome in a contemporary, modernized healthcare system. With a virtually alarming global rise of antibiotic resistance overall, nanotechnologies may prove to be the much-needed ‘lifebuoy’ that will eventually suppress this prejudicial phenomenon. This review aims to present the most promising, currently known nano-solutions, with glimpses on clinical and epidemiological aspects of the UTIs, prospective diagnostic instruments, and non-antibiotic treatments, all of these engulfed in a comprehensive overview.

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Comparison of Epidemiological Characteristics Between ESBL and Non-ESBL Isolates of Clinically Isolated Escherichia coli from 2014 to 2022: A Single-Center Study

Zhang¹,

Wang²,

Li-ru³

et al. 2023

IDR

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Purpose This single-center study aims to investigate the epidemiological characteristics of clinically isolated Escherichia coli from 2014 to 2022. Methods In vitro drug sensitivity of E. coli to 20 antibiotics was examined using the microbroth dilution method. A total of 7580 clinical E. coli strains were isolated from 2014 to 2022, among which 56.9% were identified as extended spectrum beta-lactamase-producing strains. The data were analyzed using the software WHONET5.6 and the R language platform. Results Over the study period, carbapenem resistance rates increased by more than 50% (2022 [1.34%] vs 2014 [0.8%]) and the annual number of isolates showed an upward trend (1264 in 2022 vs 501 in 2014). Drug resistance rates were the highest for penicillin (75–85%) and lowest for imipenem (1%). The resistance rate of strains isolated from male patients and sputum was found to be higher than that of female patients and urine, except for quinolones ( p <0.05). The drug resistance rates from high to low were penicillins (75–85%), tetracycline (64%), quinolones (64–67%), sulfamethoxazole (59.3%), cephalosporins (22–72%), aztreonam (34%), chloramphenicol (21%), amikacin (2.8%), colistin (1.4%), meropenem (1.1%), and imipenem (1%). Urine, sputum, and blood accounted for 51%, 16.6%, and 10.6% of the samples, respectively. A greater number of female patients were included more than male patients (4798[63.3%] vs 2782[26.7%]). Patients aged 50–80 accounted for 64.2% of those surveyed. Conclusion Carbapenems remain the optimal choice for treating extended spectrum beta-lactamase-producing E. coli infections (sensitivity rate: 98%). Colistin (87.7%) and amikacin (87%) exhibited good antibacterial activities against carbapenem-resistant E. coli . Long-term and continuous epidemiological surveillance of E. coli can facilitate the development of preventive strategies and control policies.

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Economic Burden of Urinary Tract Infections From Antibiotic-Resistant Escherichia coli Among Hospitalized Adult Patients in Lebanon: A Prospective Cohort Study

Cited by 3 publications

References 54 publications

Identifying health research in the era of COVID-19: A scoping review

Identifying health research in the era of COVID-19: A scoping review

Nanotechnology Involved in Treating Urinary Tract Infections: An Overview

Comparison of Epidemiological Characteristics Between ESBL and Non-ESBL Isolates of Clinically Isolated Escherichia coli from 2014 to 2022: A Single-Center Study

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