2023
DOI: 10.3390/nano13030555
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Nanotechnology Involved in Treating Urinary Tract Infections: An Overview

Abstract: Considered as the most frequent contaminations that do not require hospitalization, urinary tract infections (UTIs) are largely known to cause significant personal burdens on patients. Although UTIs overall are highly preventable health issues, the recourse to antibiotics as drug treatments for these infections is a worryingly spread approach that should be addressed and gradually overcome in a contemporary, modernized healthcare system. With a virtually alarming global rise of antibiotic resistance overall, n… Show more

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Cited by 4 publications
(3 citation statements)
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“…Nanoparticles, which are less than 100 nm in size, exhibit unique biological activities and have been reported to be effective in treating biofilm-resistant UTIs [109]. Due to their small size, nanoparticles can penetrate cells and deposit ultra-thin coatings on various materials.…”
Section: Biofilm Inhibition By Nanoparticlesmentioning
confidence: 99%
“…Nanoparticles, which are less than 100 nm in size, exhibit unique biological activities and have been reported to be effective in treating biofilm-resistant UTIs [109]. Due to their small size, nanoparticles can penetrate cells and deposit ultra-thin coatings on various materials.…”
Section: Biofilm Inhibition By Nanoparticlesmentioning
confidence: 99%
“…In recent years, nanotechnology has impacted drug research and the creation of more robust and efficient medications for urinary tract infections [7][8][9]. With a diameter of up to 1000 nm, nanoparticles (NPs) are intricate, three-dimensional structures intended to produce various outcomes.…”
Section: Introductionmentioning
confidence: 99%
“…In their review, Morris et al also highlight the fact that while an intravesical approach to drug delivery is promising and has attracted the interest of clinicians, a better delivery system needs to be developed, as drug delivery through standard drainage catheters carries a high risk of infection [4]. While several groups have investigated the use of functionalized antimicrobial particles suitable for intravesical treatment of UTI, and some have attempted to improve antibiotic instillation using nano-sized delivery platforms, none of these approaches have been approved for this use [5][6][7]. However, in light of the evidence supporting the use of the intravesical route of antibiotic administration, as outlined by authors in this review, there is a significant need for investment in novel technologies to enable controlled and targeted delivery of antibiotics.…”
mentioning
confidence: 99%