Economic evidence of influenza vaccination in children

Savidan, Emmanuelle; Chevat, Catherine; Marsh, Grenville

doi:10.1016/j.healthpol.2007.09.009

Cited by 28 publications

(16 citation statements)

References 44 publications

(115 reference statements)

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“…These evaluations have shown that influenza vaccination of children is cost-effective and may even be cost-saving [38,39]. However, most of the previous simulation studies have lacked consideration of herd immunity effects.…”

Section: Discussionmentioning

confidence: 99%

The epidemiological impact of childhood influenza vaccination using live-attenuated influenza vaccine (LAIV) in Germany: predictions of a simulation study

et al. 2014

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BackgroundRoutine annual influenza vaccination is primarily recommended for all persons aged 60 and above and for people with underlying chronic conditions in Germany. Other countries have already adopted additional childhood influenza immunisation programmes. The objective of this study is to determine the potential epidemiological impact of implementing paediatric influenza vaccination using intranasally administered live-attenuated influenza vaccine (LAIV) in Germany.MethodsA deterministic age-structured model is used to simulate the population-level impact of different vaccination strategies on the transmission dynamics of seasonal influenza in Germany. In our base-case analysis, we estimate the effects of adding a LAIV-based immunisation programme targeting children 2 to 17 years of age to the existing influenza vaccination policy. The data used in the model is based on published evidence complemented by expert opinion.ResultsIn our model, additional vaccination of children 2 to 17 years of age with LAIV leads to the prevention of 23.9 million influenza infections and nearly 16 million symptomatic influenza cases within 10 years. This reduction in burden of disease is not restricted to children. About one third of all adult cases can indirectly be prevented by LAIV immunisation of children.ConclusionsOur results demonstrate that vaccinating children 2–17 years of age is likely associated with a significant reduction in the burden of paediatric influenza. Furthermore, annual routine childhood vaccination against seasonal influenza is expected to decrease the incidence of influenza among adults and older people due to indirect effects of herd protection. In summary, our model provides data supporting the introduction of a paediatric influenza immunisation programme in Germany.

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Section: Discussionmentioning

confidence: 99%

The epidemiological impact of childhood influenza vaccination using live-attenuated influenza vaccine (LAIV) in Germany: predictions of a simulation study

et al. 2014

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“…Vaccinating children has the potential to reduce influenza episodes both in the vaccinated individuals, but also in individuals of all age groups who were not vaccinated, or who did not successfully seroconvert following vaccination. Several countries now offer annual influenza vaccination to healthy children as it has been repeatedly shown to be a cost-effective extension of existing national influenza vaccination programmes [15,16]. A pilot of the extended vaccination policy was implemented for the 2013-14 influenza season.…”

Section: Age Groupmentioning

confidence: 99%

Targeted vaccination in healthy school children – Can primary school vaccination alone control influenza?

Thorrington

Jit

Eames

2015

Vaccine

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“…6,7 Additionally, while data are insufficient, a recent review of the economic benefit of paediatric influenza vaccination pointed to 'an economic interest for society of vaccinating children'. 14 The first phase radio and newspaper campaign continued for a period of about 3 weeks and was timed to overlap with a school holiday break. This initial campaign produced the greatest rate of clinic attendance (Figure 4).…”

Section: Establishing and Maintaining High Vaccination Coverage Againmentioning

confidence: 99%

Marketing paediatric influenza vaccination: results of a major metropolitan trial

Buynder

Carcione

Rettura

et al. 2010

Influenza and Other Respiratory Viruses

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Please cite this paper as: Van Buynder et al. (2010) Marketing paediatric influenza vaccination: results of a major metropolitan trial. Influenza and Other Respiratory Viruses 5(1), 33–38. Objectives After a cluster of rapidly fulminant influenza related toddler deaths in a Western Australian metropolis, children aged six to 59 months were offered influenza vaccination in subsequent winters. Some parental resistance was expected and previous poor uptake of paediatric influenza vaccination overseas was noted. A marketing campaign addressing barriers to immunization was developed to maximise uptake. Design Advertising occurred in major statewide newspapers, via public poster displays and static ‘eye‐lite’ displays, via press releases, via a series of rolling radio advertisements, via direct marketing to child care centres, and via a linked series of web‐sites. Parents were subsequently surveyed to assess reasons for vaccination. Main Outcome Results The campaign produced influenza vaccination coverage above that previously described elsewhere and led to a proportionate reduction in influenza notifications in this age group compared to previous seasons. Conclusions Influenza in children comes with significant morbidity and some mortality. Paediatric influenza vaccination is safe, well tolerated and effective if two doses are given. A targeted media campaign can increase vaccine uptake if it reinforces the seriousness of influenza and addresses community ‘myths’ about influenza and influenza vaccine. The lessons learned enabling enhancements of similar programs elsewhere.

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Economic evidence of influenza vaccination in children

Cited by 28 publications

References 44 publications

The epidemiological impact of childhood influenza vaccination using live-attenuated influenza vaccine (LAIV) in Germany: predictions of a simulation study

The epidemiological impact of childhood influenza vaccination using live-attenuated influenza vaccine (LAIV) in Germany: predictions of a simulation study

Targeted vaccination in healthy school children – Can primary school vaccination alone control influenza?

Marketing paediatric influenza vaccination: results of a major metropolitan trial

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