Introduction:The level of male participation in family planning by choosing vasectomy in East Lampung region Pekalongan health centres is still low, although the success rate of vasectomy as a family planning method is very high. This study aims to explain the factors related to men's choice of vasectomy in the Pekalongan health center East Lampung. Methods: This study used an analytical study design with a cross-sectional approach. Samples were 117 men of reproductive age gathered using purposive sampling. The independent variables were knowledge, attitudes, parity, age, availability of health resources and infrastructure, health education, attitude and behaviour of health care workers and family support. The dependent variable was the men's participation in vasectomy as a family planning method. Data were retrieved using questionnaires and statistically analysed using the Chi-Square test. Results: Factors affecting the selection of vasectomy as a family planning method amongst men of reproductive age were attitude (p=0.020), parity (p=0.022), age (p=0.021), the availability of health resources and health infrastructure (p=0.018), and family support (p=0.011). However, the knowledge, health education, and the attitudes and behaviour of health workers did not affect the selection of vasectomy as a family planning method. Conclusiom: Public health centres are expected to build family planning services, especially for vasectomies, through, for example, the provision of vasectomy facilities which can reach the community and the establishment of cadres for male birth control.