In the 21st century, the study of migration processes is becoming an area of increased attention and intersection of scientific interests of economists and sociologists. Migration issues are acquiring a special role for Russia, since in modern conditions of economic development, there is a tendency for an outflow of labor resources from the regions to large administrative centers and metropolises. The main reasons for migration: economic, political and cultural-religious. Educational migration of young people may negatively affect regional labor markets in the future. The migration of the young population depends on traditional factors, within the region and between the constituent entities of the Russian Federation, as well as on specific factors that influence decision-making on the choice of place of residence. The outflow of the economically active part of the population from the "depressed" territories negatively affects the quality of management and the quality of human capital. The migration outflow of the young population against the background of depopulation has an impact on the socioeconomic state and development of the regions. In Russia, a migration policy has been developed, which should contribute to solving global problems in the field of economic and social development of the country, as well as to ensure economic security and protection of national interests. Aspects of the impact of migration processes on the economic potential are comprehensively considered by both foreign and domestic economists. The article is devoted to assessing the impact of the migration outflow of the young population on the main socio-economic indicators and economic security of the region. The statistical data of the Astrakhan region were analyzed, on the basis of which a correlation analysis was carried out, according to the results of which the regularity of the influence of the outflow of young personnel on the innovative component of the regional economy was revealed.