Ectopic Cervical Thyroid Carcinoma—Review of the Literature with Illustrative Case Series

Kłubo-Gwieździńska, Joanna; Manes, R. Peter; Chia, Stanley H.; Burman, Kenneth D.; Stathatos, Nikolaos; Deeb, Ziad E.; Wartofsky, Léonard

doi:10.1210/jc.2011-0611

Cited by 98 publications

(71 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…4,5 Thyroid cancer arising in ectopic thyroid tissue is extremely rare at less than 1%. 6 Thyroid hemiagenesis (TH) is another rare developmental abnormality with a prevalence as high as 0.2% when determined by ultrasound screening. 7 TH is more common in females and left lobe hemiagenesis comprises more than 80% of cases.…”

Section: Discussionmentioning

confidence: 99%

A Case of a Rare Association Between Right Thyroid Hemiagenesis, Lingual Thyroid, and Papillary Thyroid Cancer

Azmat¹,

Phay²,

Teknos³

et al. 2017

US Endocrinology

View full text Add to dashboard Cite

Lingual thyroid and thyroid hemiagenesis are rare thyroid developmental abnormalities. These conditions can be present with other thyroid diseases, whether functional ones involving abnormal thyroid hormone levels, or structural ones such as presence of thyroid nodules, however the association with thyroid cancer and lingual thyroid or thyroid hemiagenesis is rare. In addition to that, when thyroid hemiagenesis is present, it is usually in the left lobe. We describe here a pregnant patient who presented with metastatic cervical nodes from thyroid cancer who was found on imaging to have right thyroid hemiagenesis. After she underwent an initial surgery for thyroid cancer and metastatic nodal disease, she was then later discovered to have a lingual thyroid. In this case we report this extremely rare combination and also discuss the potential implications of this association on the diagnosis and management of these patients particularly initial surgery and imaging studies needed for the thyroid cancer.

show abstract

Section: Discussionmentioning

confidence: 99%

A Case of a Rare Association Between Right Thyroid Hemiagenesis, Lingual Thyroid, and Papillary Thyroid Cancer

Azmat¹,

Phay²,

Teknos³

et al. 2017

US Endocrinology

View full text Add to dashboard Cite

show abstract

“…Ectopic thyroid may present at lingual, sublingual, thyroglossal, pretracheal, laryngotracheal and laterocervical 9 and sometimes submandibular, retroperitoneal, and exceptionally at esophagus, mediastinum, heart, aorta, adrenal glands, pancreas, gallbladder and skin. 2,10-13 It is very rare to find orthotopic thyroid gland in coexistence with ectopic one.…”

Section: Discussionmentioning

confidence: 99%

Lingual Papillary Thyroid Carcinoma with Bilateral Neck Node Metastasis

Singh¹,

Jain²,

Das³

2017

World Journal of Endocrine Surgery

View full text Add to dashboard Cite

Incidence of ectopic thyroid tissue is 1 in every 100,000 to 300,000 in general population and lingual thyroid is the most common ectopic site (90%). The number of reported neoplasms occurring in this tissue seems disproportionately small when compared with the frequency of tumor formation in the normally placed thyroid. Till now only 51 cases of lingual thyroid cancer have been reported in the literature. We are reporting a case of lingual thyroid carcinoma with bilateral cervical metastasis and absent orthotopic thyroid gland. In our case we approach the tumor via midline lip splitting with lateral mandibulotomy approach which provides us a good exposure of the entire oropharynx (tumor). We have managed the tumor according to the guidelines of differentiated thyroid cancer because of non availability of guidelines for ectopic thyroid cancer. After surgical excision of lingual thyroid and neck dissection radioiodine therapy was given. The surgical approach to a lingual thyroid cancer as well as adjuvant therapy and natural history remains to be ascertained due to the rarity of the disease. Lip splitting with lateral mandibulotomy and swing approach appears to give adequate exposure to lingual thyroid. How to cite this article Singh SP, Das S, Jain DK. Lingual Papillary Thyroid Carcinoma with Bilateral Neck Node Metastasis. World J Endoc Surg 2017;9(2):68-71.

show abstract

“…The majority of carcinomas arise from salivary gland or thyroid tissue [26][27][28]. Heterotopia-associated thyroid carcinoma may arise in ectopic thyroid tissue (lingual, tracheal, midline, or lateral neck) or branchial cleft or thyroglossal duct cysts.…”

Section: Heterotopia-associated Carcinomamentioning

confidence: 99%

“…Histologically, papillary thyroid carcinoma is the most common type thyroid carcinoma seen in heterotopic sites. Other types include: follicular carcinoma, Hurthle cell carcinoma, anaplastic thyroid carcinoma, and medullary carcinoma [28]. About 80% of tumors arising in heterotopic salivary gland are benign such as Warthin's tumor and pleomorphic adenoma.…”

Section: Heterotopia-associated Carcinomamentioning

confidence: 99%

See 1 more Smart Citation

Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: What Is New in the 2017 WHO Blue Book for Tumors and Tumor-Like Lesions of the Neck and Lymph Nodes

Katabi

Lewis

2017

Head and Neck Pathol

View full text Add to dashboard Cite

show abstract

Ectopic Cervical Thyroid Carcinoma—Review of the Literature with Illustrative Case Series

Cited by 98 publications

References 65 publications

A Case of a Rare Association Between Right Thyroid Hemiagenesis, Lingual Thyroid, and Papillary Thyroid Cancer

A Case of a Rare Association Between Right Thyroid Hemiagenesis, Lingual Thyroid, and Papillary Thyroid Cancer

Lingual Papillary Thyroid Carcinoma with Bilateral Neck Node Metastasis

Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: What Is New in the 2017 WHO Blue Book for Tumors and Tumor-Like Lesions of the Neck and Lymph Nodes

Contact Info

Product

Resources

About