Ectopic Non Functional Pituitary Adenoma – A Case Report

Mittal, Richa; Bahal, Neelima; Azad, Sheenam; Acharya, Seema; Mittal, Umesh Kumar

doi:10.32677/ijcr.2020.v06.i02.017

Cited by 1 publication

(2 citation statements)

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“…It is worth noting that ectopically deposited cells have the infrequent potential to give rise to adenomas at various locations along this migratory pathway [ 1 , 9 , 10 ]. Since its first description by Erdheim in 1909, several ectopic sites have been reported, namely, sphenoid sinus, clivus, parapharyngeal space, nasal cavity, nasopharynx, third ventricle, and suprasellar region [ 2 , 4 , 11 ]. These rare neoplasms have a minor female predominance (1.3 : 1) with most patients presenting in the 6 th decade [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

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Null-Cell Ectopic Pituitary Adenoma of the Nasal Cavity

Figaro,

Juman,

Ramsundar

et al. 2023

Case Reports in Otolaryngology

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An ectopic pituitary adenoma (EPA) is an uncommon type of pituitary adenoma, accounting for only 2% of all pituitary adenomas. EPAs are benign tumors that can occur anywhere along the migratory embryonic path of the pituitary gland and have no relationship to intrasellar elements. They are usually hormonally active and have a minor female predominance. The clinical features of EPAs are highly dependent on its hormonal activity, anatomical location, and its local mass effect. Appropriate radiological imaging is essential for the evaluation of EPAs. Imaging investigations show a normal pituitary gland and sellar turcica, provide details on the size of the tumor, its margins, and extent, and help with surgical planning. The criteria for diagnosing an ectopic pituitary adenoma depend on detailed histopathological examination. EPA management should be individualized. We present a case of a 71-year-old male who presented with a 9-month history of left nasal obstruction, purulent nasal discharge, and intermittent anterior epistaxis. The patient was being managed by his general practitioner for chronic rhinosinusitis but failure of his symptoms to resolve prompted a visit to the otorhinolaryngologist. The patient was diagnosed with a null-cell ectopic pituitary adenoma through histological analysis of a biopsy specimen that showed adenohypophyseal cells without cell-type-specific differentiation. The patient subsequently underwent an endoscopic endonasal excision and had an uneventful hospital stay.

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Section: Discussionmentioning

confidence: 99%

“…They are commonly classified based on their size, hormone secreting capacity, and location within the gland. Ectopic pituitary adenomas, in contrast, are uncommon, making up just 2% of all pituitary adenomas [ 2 ]. Ectopic pituitary adenomas are completely extrasellar and have no relationship to intrasellar elements [ 3 ].…”

Section: Introductionmentioning

confidence: 99%