The
(
n
,
k
)‐arrangement graph
A
(
n
,
k
) with
1
≤
k
≤
n
−
1, is the graph with vertex set the ordered
k‐tuples of distinct elements in
{
1
,
2
,
…
,
n
} and with two
k‐tuples adjacent if they differ in exactly one of their coordinates. The
(
n
,
k
)‐arrangement graph was proposed by Day and Tripathi in 1992, and is a widely studied interconnection network topology. The Johnson graph
J
(
n
,
k
) with
1
≤
k
≤
n
−
1, is the graph with vertex set the
k‐element subsets of
{
1
,
2
,
…
,
n
}, and with two
k‐element subsets adjacent if their intersection has
k
−
1 elements. In 1989, Brouwer, Cohen and Neumaier determined the automorphism group of
J
(
n
,
k
), and in 2015, Dobson and Malnič proved that
J
(
n
,
k
) a is Cayley graph if and only if
(
n
,
k
)
=
(
8
,
3
),
(
32
,
3
) or
(
n
,
2
) with
n
≡
3
(
sans-serifmod
4
) being a prime‐power. In this article we prove that
sans-serifAut
(
A
(
n
,
k
)
)
≅
S
n
×
S
k, and as a byproduct,
A
(
n
,
k
) is a normal cover of
J
(
n
,
k
). Furthermore,
A
(
n
,
k
) is a Cayley graph if and only if
(
n
,
k
)
=
(
33
,
4
),
(
11
,
4
),
(
9
,
4
),
(
12
,
5
),
(
8
,
5
),
(
9
,
6
),
(
32
,
29
),
(
33
,
30
),
(
n
,
1
),
(
n
,
n
−
1
),
(
n
,
n
−
2
),
(
q
,
2
) or
(
q
+
1
,
3
), where
q is a prime‐power. Note that the graph
A
(
n
,
n
−
1
) is called the
n‐star graph, and its automorphism group can be deduced from a general result given by Feng in 2006. In 1998, Chiang and Chen proved that
A
(
n
,
n
−
2
) is a Cayley graph on the alternating group
A
n, and in 2011, Zhou determined the automorphism group of
A
(
n
,
n
−
2
).