Educational difference in the prevalence of osteoporosis in postmenopausal women: a study in northern Iran

Maddah, Mohsen; Sharami, Seyedeh Hajar; Karandish, Majid

doi:10.1186/1471-2458-11-845

Cited by 22 publications

(19 citation statements)

References 13 publications

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“…BMD is a valuable clinical diagnostic index for osteoporosis and the best tool for osteoporotic fracture prediction. 7 - 10 Osteoporosis is associated with several genetic and nongenetic factors, 1 , 3 some of which include age, 1 , 11 - 14 sex, 1 - 3 menopausal status, 1 - 3 , 15 educational level, 11 , 12 , 14 , 16 coffee drinking, 11 smoking, 1 , 2 , 12 exercise, 1 , 2 , 12 alcohol consumption, 1 , 2 , 12 diet, 1 , 2 , 17 and body mass index (BMI). 1 , 11 , 13 , 14 , 18 …”

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confidence: 99%

Association between osteoporosis and menopause in relation to SOX6 rs297325 variant in Taiwanese women

et al. 2020

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Objective: Osteoporosis, the most prevalent bone disorder in humans, is a global public health issue and its relationship with menopause is well-established. The interaction between menopause and genes on osteoporosis risk is, however, yet to be fully elucidated. We assessed the association between menopause and osteoporosis in relation to the SOX6 rs297325 variant in Taiwanese women. Methods: There were 7,581 female participants, aged 30 to 70 years old. Information on SOX6 rs297325 and menopause were obtained from the Taiwan Biobank Database while that on osteoporosis was obtained from the National Health Insurance Research Database. Results: Menopause but not SOX6 rs297325 was significantly associated with a higher risk of osteoporosis (odds ratio [OR] = 1.48; 95% confidence interval [CI] = 1.04-2.10). The interaction between menopause and rs297325 on osteoporosis was significant ( P = 0.0216). After stratification by rs297325 genotypes, the risk of osteoporosis was significantly higher in menopausal women having the TT + CC genotype (OR = 2.02; 95% CI = 1.21-3.38). After stratification by menopausal status and rs297325 genotypes, the OR; 95% CI was 0.62; 0.38 to 0.99 in premenopausal women with the TC + CC genotype and 1.24; 0.82 to 1.88 in menopausal women with the TC + CC genotype. Conclusion: SOX6 rs297325 was not significantly associated with osteoporosis but might have modulated the association between menopause and osteoporosis. The risk of osteoporosis was higher in menopausal women with the TC + CC genotype but lower in premenopausal women with the TC + CC genotype.

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confidence: 99%

Association between osteoporosis and menopause in relation to SOX6 rs297325 variant in Taiwanese women

et al. 2020

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“…OP was considerably prevalent among women of low social status than those living in urban areas [59]. At all BMD sites, women under absolute poverty lines had the lowest BMD [59].…”

Section: Modifiable Risk Factorsmentioning

confidence: 90%

“…OP was considerably prevalent among women of low social status than those living in urban areas [59]. At all BMD sites, women under absolute poverty lines had the lowest BMD [59]. According to the WHO definition, 22.4% of subjects under absolute poverty lines and 8.7% healthy postmenopausal women were considered osteoporotic [60].…”

Section: Modifiable Risk Factorsmentioning

confidence: 99%

“…According to the WHO definition, 22.4% of subjects under absolute poverty lines and 8.7% healthy postmenopausal women were considered osteoporotic [60]. Low education was associated with lower BMD and a higher prevalence of OP even after controlling for strong confounders (age, BMI, physical activity) [18,59,61]. Nevertheless, in another study, there was no significant association between OP and educational level [28].…”

Section: Modifiable Risk Factorsmentioning

confidence: 99%

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Epidemiology and awareness of osteoporosis: a viewpoint from the Middle East and North Africa

Hammam¹

2018

Int. J. Clin. Rheumatol

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Background: Osteoporosis (OP) is defined by low bone mass and microstructural deterioration. It is an escalating public health problem due to increase life expectancy and the resulting bone fractures represent a significant burden for both the individual and the society in terms of morbidity, mortality and cost. Osteoporosis, a multifactorial disease, results from the interaction between genetic and environmental risk factors. Currently, the data available regarding OP epidemiology and predisposing risk factors differ greatly between regions and within population ethnicities. Proper estimation of the epidemiology of OP and its health related outcomes can help identity those at risk and permit prophylactic treatment before its occurrence. The main barrier towards disease prevention strategies is the impaired awareness of the disease and its risk. Enhanced understanding of the OP disease may influence personal behaviors and reduce its prevalence.Objectives: This review was undertaken to wrap-up and throw-light on the published literatures related to the epidemiology of osteoporosis in the Middle East and North Africa (MENA) region, and expose the extent of awareness in the corresponding populations. Describing and discussing key points on the current state of knowledge on these hot issues are well thought-out.Conclusion: Osteoporosis prevalence is variable among MENA populations. Limited reports regarding the established prevalence of osteoporotic fractures among those populations and therefore, lack of guidelines for prevention and management were noticed. In order to improve bone health, preventive measures against OP should be considered. Increase OP awareness and preventive practices in the societies as part of the prophylactic strategy need to be initiated.

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“…Beberapa faktor risiko tersebut diduga lebih umum terjadi pada orang dengan tingkat pendidikan yang rendah. 11 Tingkat pendidikan dapat memengaruhi kemampuan seseorang dalam menyerap dan menerima informasi kesehatan dan gizi, serta kemampuan berperan serta dalam mewujudkan status kesehatan dan gizi yang baik. Penelitian lain menyimpulkan bahwa tingkat pendidikan yang lebih tinggi secara independen berkaitan dengan DMT yang lebih baik dan prevalensi osteoporosis yang lebih rendah pada wanita postmenopause di Cina.…”

Section: Hasilunclassified

Gangguan Kepadatan Tulang pada Orang Dewasa di Daerah Urban dan Rural

Mardiyah

Sartika

2014

Kesmas: National Public Health Journal

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Gangguan kepadatan tulang atau osteoporosis dan osteopenia merupakan masalah kesehatan masyarakat utama yang disebabkan oleh banyak faktor. Tujuan dari penelitian ini adalah mengetahui berbagai faktor yang berhubungan dengan gangguan kepadatan tulang pada kelompok usia dewasa di daerah urban dan rural terpilih di Provinsi Jawa Barat tahun 2012. Desain penelitian yang digunakan adalah potong lintang dengan sampel 142 responden. Penelitian dilakukan pada bulan Mei - Juni 2012 di Pesona Khayangan, Kecamatan Sukmajaya, Kota Depok, sebagai daerah urban dan Desa Pabuaran, Kecamatan Gunung Sindur, Kabupaten Bogor sebagai daerah rural. Prevalensi gangguan kepadatan tulang dalam penelitian ini adalah sekitar 31,7% (4,2% osteoporosis dan 27,5% osteopenia). Analisis multivariat menemukan responden yang mempunyai indeks massa tubuh (IMT) < 23,49 kg/m2 berisiko mengalami gangguan kepadatan tulang 5,5 kali lebih tinggi daripada responden dengan IMT > 27,36 kg/m2. Responden yang mempunyai IMT 23,49 _ 27,36 kg/m2 berisiko mengalami gangguan kepadatan tulang 2,2 kali lebih tinggi daripada responden yang mempunyai IMT > 27,36 kg/m2 setelah dikontrol variabel usia, asupan vitamin D, dan asupan protein. Pada penelitian ini, IMT merupakan faktor yang paling berhubungan dengan gangguan kepadatan tulang setelah dikontrol variabel usia, asupan vitamin D, dan asupan protein. Semakin rendah IMT,maka semakin tinggi risiko gangguan kepadatan tulang.Bone density disorder (osteoporosis and osteopenia) is a major public health problem caused by multifactor. The purpose of this study was to find out factors related to adult bone density disorder in the selected urban and rural area, West Java Province, 2012. It used cross-sectional method and the samples were 142 respondents. The data was taken from 2012 May to June in Pesona Khayangan, Kecamatan Sukmajaya, Kota Depok as the urban area and Desa Pabuaran, Kecamatan Gunung Sindur, Kabupaten Bogor as the rural area. Prevalence of bone density disorder in this study was 31.7% (4.2% osteoporosis and 27.5% osteopenia). Multivariate analysis verified that respondent with body mass index (BMI) < 23.49 kg/m2 will 5.5 times higher to have bone density disorder than respondent with BMI > 27.36 kg/m2. Respondent with BMI 23.49 _ 27.36 kg/m2 will 2.2 times higher to have bone density disorder than respondent with BMI > 27.36 kg/m2 after controlled by age, vitamin D and protein intake variable. In this study, BMI is the most related factor of bone density disorder after controlled by age, vitamin D and protein intake variable. The lower BMI, the higher risk of bone density disorder.

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Educational difference in the prevalence of osteoporosis in postmenopausal women: a study in northern Iran

Cited by 22 publications

References 13 publications

Association between osteoporosis and menopause in relation to SOX6 rs297325 variant in Taiwanese women

Association between osteoporosis and menopause in relation to SOX6 rs297325 variant in Taiwanese women

Epidemiology and awareness of osteoporosis: a viewpoint from the Middle East and North Africa

Gangguan Kepadatan Tulang pada Orang Dewasa di Daerah Urban dan Rural

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