Efek Samping Kemoterapi Berbasis Karboplatin Terhadap Fungsi Ginjal Pada Pasien Kanker Ginekologi

Chemotherapy for Leukemia Children on Elevated Creatinine Ureum Levels

“…Based on the results of data analysis in the bivariate test, it was found that there was no increase in creatinine urea levels after leukemia chemotherapy in children. The results of this study are in line with research conducted by Djoko Heri Hermanto who obtained the results of the Wilcoxon test which found no significant increase in pre and post chemotherapy BUN levels (Hermanto et al, 2021;Hoeben et al, 2022). In several studies on the picture of kidney function with acute lymphoblastic leukaemia therapy, it was seen that the picture of kidney function in children with lymphoblastic leukaemia therapy in the high risk group and the standard risk group after undergoing consolidation phase chemotherapy had no significant difference.…”

“…Renal complications that occur in patients with LLA are often attributed to several factors, namely the infiltration of leukaemia cells into the kidney cells and also due to the effect of treatment on the cancer cells themselves (Hermanto et al, 2021;Queudeville & Ebinger, 2021). Complications to the kidneys are not uncommon and mostly occur in the induction phase, and can last for several years or may even become permanent.…”