Tourism undergoes a cycle of change so that it affects the culture-based Balinese tourism model through strengthening local wisdom. Tourism will be able to run optimally if it has guarantees, cultural resilience, because in addition to functioning as a tourist attraction, tourism is considered a medium to reap large profits, so that tourism activities often shift cultural values and change people's lifestyles. For this reason, in an effort to control the influence of globalization on industrialization investment in tourism which has begun to follow the changes in the civilization of the industrial revolution 4.0, Badung Regency has become the rule model for the transformation of the implementation of culture-based tourism investment. This research study is descriptive-analytical in nature, which is a type of research that does not stop at mere descriptions but also comes to an effort to study the characteristics of solving cases of tourism investment problems using qualitative research methods. The results of this study indicate that the understanding of the people of Badung Regency on the importance of the value of local wisdom in the application of a culture-based investment model is very high so that investment activities in the tourism sector not only emphasize aspects of the national economy but also the preservation of local wisdom. In addition, the application of a culture-based investment model with strengthening local wisdom requires good synergy between the Government, Indigenous Village communities, tourism businesses and investors so that they can truly develop the concept of sustainable cultural tourism in Bali.