EFEKTIVITAS ANALGETIK EKSTRAK ETANOL AKAR ALANG-ALANG (Imperata cylindrica (L) Beauv ) PADA MENCIT PUTIH JANTAN

Abstract

Pain is an unpleasant sensory and emotional experience due to tissue damage, either actual or potential or described in the form of damage. Provision of therapeutic doses of analgesics relieve pain or suppress. Plants Imperata cylindrica L. Beauv empirically used as traditional medicine. The purpose of this study to know the analgetic effect of root ethanol extract of alang-alangImperata cylindrica L. Beauv.
 This study was done by infra red (IR) plantar test method with a wavelength of 96 nm. Twenty male mice were divided into 4 groups. Three groups were given ethanol extract of Imperata cylindrica L. Beauv branches at a doses of 15 mg/kg bb, 30 mg/kg bb 60 mg/kg bb and one group was given 0,5% CMC Na (control) orally. After that, the time (second) hold infra red induction of pain every 10 minutes to 60 minutes. The data obtained were processed using one-way analysis of variance (ANOVA) and followed test the level of 95%.
 The results of phytochemical screening Imperata cylindrica L. Beauv is alkaloid, flavonoid, and steroid/triterpenoid. Ethanol extract Imperata cylindrica L. Beauv dose of 15 mg/kg bb average induction able to withstand pain of 12,86; 14,34; 15,44; 19,2; 17,52; 15,42 second, the dose of 30 mg/kg bb 13,6; 17,08; 19,82; 18,44; 16,9; 16,48 second, and a dose of 60 mg/kg bb 16,96; 18,9; 18,94; 22,14; 18,0; 17,26 second.
 Pain is an unpleasant sensory and emotional experience due to tissue damage, either actual or potential or described in the form of damage. Provision of therapeutic doses of analgesics relieve pain or suppress. Plants Imperata cylindrica L. Beauv empirically used as traditional medicine. The purpose of this study to know the analgetic effect of root ethanol extract of alang-alangImperata cylindrica L. Beauv.
 This study was done by infra red (IR) plantar test method with a wavelength of 96 nm. Twenty male mice were divided into 4 groups. Three groups were given ethanol extract of Imperata cylindrica L. Beauv branches at a doses of 15 mg/kg bb, 30 mg/kg bb 60 mg/kg bb and one group was given 0,5% CMC Na (control) orally. After that, the time (second) hold infra red induction of pain every 10 minutes to 60 minutes. The data obtained were processed using one-way analysis of variance (ANOVA) and followed test the level of 95%.
 The results of phytochemical screening Imperata cylindrica L. Beauv is alkaloid, flavonoid, and steroid/triterpenoid. Ethanol extract Imperata cylindrica L. Beauv dose of 15 mg/kg bb average induction able to withstand pain of 12,86; 14,34; 15,44; 19,2; 17,52; 15,42 second, the dose of 30 mg/kg bb 13,6; 17,08; 19,82; 18,44; 16,9; 16,48 second, and a dose of 60 mg/kg bb 16,96; 18,9; 18,94; 22,14; 18,0; 17,26 second.

Pemanfaatan Tumbuhan Alang-Alang (Imperata Cylindrica L) sebagai Obat Tradisional oleh Masyarakat Desa Selasi Kabupaten Buru Selatan

“…Akar kaku berbuku-buku dan menjalar. Tunas muda bisa dimakan dan sangat bermanfaat untuk anak-anak (Kartika et al, 2020).…”

“…Hal tersebut sejalan dengan pendapat yang dikemukakan oleh Balai POM bahwa untuk meningkatkan mutu suatu obat tradisional, maka pembuatan obat tradisional haruslah dilakukan dengan sebaik-baiknya mengikutkan pengawasan menyeluruh yang bertujuan untuk menyediakan obat tradisional yang senantiasa memenuhi persyaratan yang berlaku. Keamanan dan mutu obat tradisional tergantung dari bahan baku, bangunan, prosedur, dan pelaksanaan pembuatan, peralatan yang digunakan, pengemasan termasuk bahan serta personalia yang terlibat dalam pembuatan obat tradisional (Kartika et al, 2020).…”

PEMANFAATAN ALANG-ALANG (Imperata Clyndrica ) SEBAGAI PANGAN FUNGSIONAL JELLY DRINK (KAJIAN: JENIS DAN KONSENTRASI GELLING AGENT)

“…Flavonoid berpotensi untuk mengurangi rasa nyeri dengan menghambat kerja enzim siklooksigenase (Safwan dkk.,2016). Berdasarkan penelitian Mulyadi, dkk (2013) dalam Kartika (2020), menunjukkan bahwa akar, daun dan bunga alang-alang berpotensi dalam menghambat pertumbuhan bakteri Escherichia coli, Pseudomonas aeroginosa, Bacillus subtilis dan Staphylococcus aureus.…”

Studies on the Benefits of Cogon Grass (Imperata cylindrica L) in Indonesia: A Review

“…The results of pharmaceutical studies of cogon grass show that cogon grass extract has the following properties: Anticancer [27] , antilithiasis [28][29] , antioxidant [30][31][32][33] , antipyretic [35][36] , analgesic [37] , anti-inflammatory [38][39] , antilarvae [41][42] . In other studies, related to health, cogon gras extract is known to reduce male fertility [44,46] , increase antibodies [47] , increase male stamina [49] , and increase body weight [50] .…”