Effect of a 0.05% Neutral NaF Mouthrinse on Coronal and Root Caries of Adults¹

Abstract

Three‐year coronal and root caries increments were compared in adults rinsing with either a 0.05% neutral NaF mouthrinse or a placebo mouthrinse. 1006 subjects, initially 20–65 years old (mean age: 39.9 yrs). who resided in fluoride deficient communities used a fluoride or placebo mouthrinse daily in their homes and brushed with an A.D.A. accepted fluoride dentifrice provided by the study. After three years, 731 subjects remained. Compliance was good. There were no significant differences (t‐test, p≤ 0.05) in coronal DMFT, coronal DMFS, root DFT and root DFS between the two groups. In subjects exhibiting root caries at the final examination, the DF root surface increment was 25.1% less in the fluoride mouthrinse users compared to those using the placebo rinse, but this difference was not statistically significant. The only significant difference in the caries increment between the two study groups was found for the mesio‐distal root surfaces of 45–65 year old participants.

Systematic Review on Noninvasive Treatment of Root Caries Lesions

“…Self-applied AmF/ SnF (Ripa et al 1987;Wallace et al 1993;Fure et al 1998;Wyatt and MacEntee 2004). Compared with a respective placebo varnish, professionally applied 1% or 10% CHX varnish (MD = −0.67; 95% CI = −1.01, −0.32; Banting et al 2000;Baca et al 2009;Tan et al 2010) −0.39, −0.28; Tan et al 2010;Zhang et al 2013) reduced initiation of RCLs significantly.…”

“…Concurrently, one of the studies (Ripa et al 1987) observed no significant differences in 3-y coronal DMFS increments. In contrast, a previous review revealed a significantly lower coronal caries incidence for additional fluoride rinse, as compared to placebo or nonrinsing (Marinho et al 2003).…”

“…The median (25th/75th percentiles) follow-up time was 15 (12/24) mo. Eleven studies investigated dentifrices (Jensen and Kohout 1988;Banoczy and Nemes 1991;Baysan et al 2001;Paraskevas et al 2004;Papas et al 2007;Papas et al 2008;Vered et al 2009;Ekstrand et al 2013;Hu et al 2013;Souza et al 2013;Srinivasan et al 2013), 10 rinses (Ripa et al 1987;Banoczy and Nemes 1991;Ravald and Birkhed 1992;Wallace et al 1993;Fure et al 1998;Powell et al 1999;Paraskevas et al 2004;Wyatt and MacEntee 2004;Petersson et al 2007;Wyatt et al 2007), 8 varnishes (Schaeken et al 1991;Ravald and Birkhed 1992;Powell et al 1999;Banting et al 2000;Baca et al 2009;Fure and Lingstrom 2009;Tan et al 2010;Zhang et al 2013), 3 (fluoride) solutions (Fure and Lingstrom 2009;Tan et al 2010;Zhang et al 2013), 3 gels (Ravald and Birkhed 1992;DePaola 1993;Wallace et al 1993), 2 ozone applications (Holmes 2003;Baysan and Lynch 2007), and 1 preventive dental regimes (Mojon et al 1998). Eleven studies investigated both initiation of RCLs and the change of RCLs, 11 analyzed the change of RCLs, and 8 studied initiation of RCLs ...…”

“…Eleven studies investigated both initiation of RCLs and the change of RCLs, 11 analyzed the change of RCLs, and 8 studied initiation of RCLs compared with baseline. The initiation of RCLs and their inactivation were described most often on the basis of surface texture (13 studies: Schaeken et al 1991;Mojon et al 1998;Baysan et al 2001;Holmes 2003;Baysan and Lynch 2007;Papas et al 2007;Petersson et al 2007;Fure and Lingstrom 2009;Petersson et al 2011;Ekstrand et al 2013;Hu et al 2013;Souza et al 2013;Srinivasan et al 2013), DFMRS/DFRS (12 studies: Ripa et al 1987;Jensen and Kohout 1988;Schaeken et al 1991;Ravald and Birkhed 1992;DePaola 1993;Wallace et al 1993;Fure et al 1998;Powell et al 1999;Wyatt and MacEntee 2004;Baca et al 2009;Tan et al 2010;Zhang et al 2013), ECM (electrical caries monitor; 5 studies: Baysan et al 2001;Baysan and Lynch 2007;Petersson et al 2007;Petersson et al 2011;Hu et al 2013), or RCI (4 studies: Banoczy and Nemes 1991;Wyatt and MacEntee 2004;Baca et al 2009;Vered et al 2009); only 8 studies used more than 1 assessment to describe RCLs. A detailed summary of included studies can be found in Appendix Tables 2 and 3.…”

Cohort Study on Incidence of Coronal and Root Caries in Japanese Adults

“…Ripa et al 6) compared the incidence of coronal and root caries in patients aged 18 to 65 years over a 3-year period between an NaF mouth-rinse group and a placebo (nonmouth-rinse) group. The results revealed that the mean number of coronal decayed, missing, or filled tooth surfaces (DMFS) was 2.43, and that the mean number of root DFS was 0.43 in the placebo group.…”