Effect of a late evening meal on nitrogen balance in patients with cirrhosis of the liver.

Swart, G.R.; Zillikens, M. Carola; Vuure, J. K. Van; Berg, J. van den

doi:10.1136/bmj.299.6709.1202

Cited by 168 publications

(101 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Theoretically, LES should shorten nocturnal fasting. In the previous studies with cirrhosis patients, LES has been shown to improve fuel utilization (Chang et al, 1997;Verboeket-van de Venne et al, 1995) and nitrogen economy (Zillikens et al, 1993;Swart et al, 1989). Late evening snack with liquid nutrient (Ensure Liquid) increased RQ and carbohydrate oxidation rates (Miwa et al, 2000).…”

Section: Discussionmentioning

confidence: 97%

Effect of late evening snack with rice ball on energy metabolism in liver cirrhosis

et al. 2006

View full text Add to dashboard Cite

Objective: This study investigates the effects of a late evening snack (LES), of 200 kcal of rice ball, on energy metabolism in cirrhotic patients. Impaired nutritional metabolism has been associated with cirrhosis, and frequent intake of small meals may prevent early-onset starvation, and maintain nourishment in these patients. Subjects: Twenty-one cirrhotic patients and 26 control subjects (Control) were recruited for this study. Patients were subsequently treated by LES (LC-LES) and by a non-LES regimen (LC-NLES).Method: Resting energy expenditure and respiratory quotient (RQ) were assessed by indirect calorimetry at 0830, 1130 and 1430. Blood glucose and non-esterified fatty acids (NEFA) were measured just before the energy metabolism measurements. The regular diet included three major meals and LES, at 0900, 1200, 1800 and 2100, respectively. The Control and LC-NLES groups received only the major meals, whereas the LC-LES group received three meals plus 200 kcal LES for 7 days. There was no difference in the total energy intake among Control, LC-NLES and LC-LES groups. Results: Respiratory quotient in LC-NLES was significantly lower than that of Control at 0830. Respiratory quotient value in LC-LES significantly elevated from that in LC-NLES. The RQ values did not differ among Control, LC-NLES and LC-LES at 2 h after the meal (1130 and 1430). Non-esterified fatty acids in LC-LES were lower than that in LC-NLES after overnight fasting. Conclusions: The ingestion of a 200 kcal rice ball LES can improve the nutritional metabolism in cirrhotic patients.

show abstract

Section: Discussionmentioning

confidence: 97%

Effect of late evening snack with rice ball on energy metabolism in liver cirrhosis

et al. 2006

View full text Add to dashboard Cite

show abstract

“…Nutritional recommendations for cirrhotic patients with HE should follow ISHEN practice consensus recently published by Amodio et al 15 These recommendations, including specific pattern of dietary intake, 133,134 which should also be based on individual nutritional assessment, are summarized in Table 2.…”

Section: Nutritional Recommendations For He In Cirrhosismentioning

confidence: 99%

Nutrition in the Management of Cirrhosis and its Neurological Complications

Bémeur

Butterworth

2014

Journal of Clinical and Experimental Hepatology

View full text Add to dashboard Cite

“…Nitrogen balance was shown to become more positive in a group of cirrhotics receiving a later evening meal [31]. Total enteral nutrition can favourably influence outcome in cirrhotics.…”

Section: Discussionmentioning

confidence: 94%

“…Furthermore, in cirrhotic patients, Child grade and hospital mortality can be improved by nasogastric feeding [5]. Nitrogen balance can also be improved in cirrhotics simply by the addition of a late evening meal [31].…”

Section: Introductionmentioning

confidence: 99%

A prospective study on the effect of recipient nutritional status on outcome in liver transplantation

Harrison

McKiernan

Neuberger

1997

Transplant International

View full text Add to dashboard Cite

In a prospective study, we have examined the effect of nutritional status, using anthropometric measurement, on outcome in 102 consecutive adult patients undergoing elective orthotopic liver transplantation. Mid-arm muscle circumference was calculated from these two measurements. Patient outcome variables were time spent in the intensive therapy unit, total time in hospital, infective complications and mortality within 6 months. Graft outcome variables were early graft function, peak aspartate transaminase, alkaline phosphatase, bilirubin and prothrombin time. Group A patients were below and group B patients above the 25th percentile for mid-arm circumference and triceps skin fold thickness. Eighty-four patients (79 %) were at or below the 25th percentile of anthropometric measurements and 30 patients (28 %) were below the 5th percentile. The median mid-arm muscle circumference in group A was 22.3 (range 16.4-28.9) cm and 25.7 (range 21.7-31.8) cm in group B. The medial albumin level was similar in the two groups. There were significantly more bacterial infec- tions in group A (27/84,32 YO) than in group B (2/22,8 %; x2 = 5.4, P = 0.02). There was a difference in mortality up to 6 months post-operatively that failed to reach statistical significance (Wilcoxon-Gehan statistic -199, P = 0.09). There were 11/84 (13 Yo) deaths in group A and no deaths in group B (x2 = 2.8, P = 0.09). Post transplantation, there were significant differences (Kruskal-Wallis Anova) between groups A and B for peak alkaline phosphatase (683 vs 334 IUD, P = 0.05) and peak prothrombin time [16 (range 13-25) vs 19.5 (range 12-65), P = 0.031. These data suggest that a significant proportion of patients undergoing liver transplantation are nutritionally compromised and that this has effects on patient infection, susceptibility, graft function and mortality, which may possibly be improved by nutritional intervention.

show abstract

Effect of a late evening meal on nitrogen balance in patients with cirrhosis of the liver.

Cited by 168 publications

References 6 publications

Effect of late evening snack with rice ball on energy metabolism in liver cirrhosis

Effect of late evening snack with rice ball on energy metabolism in liver cirrhosis

Nutrition in the Management of Cirrhosis and its Neurological Complications

A prospective study on the effect of recipient nutritional status on outcome in liver transplantation

Contact Info

Product

Resources

About