Effect of a Paramunity Inducer on Reproductive Performance of Gilts

Abstract

Optimal reproductive performance of gdts is an economically important characteristic which is influenced amongst others by the general health condition of the animal. In the present pilot study, we examined whether reproductive performance of gdts that were transported from a breeding to a commercial farm can be improved by paramunization, e.g. by enhancing the non-specific immunological response of the animal. Three groups of gdts were submitted to various treatments as follows. The first group received no treatment and served as the control group. The gdts of the second group were injected twice with a paramunity inducer derived from a sheep parapoxvirus (Baypamun liquid, Bayer, Germany), once 2 days before the transport and a second time 2 h before departure. The gtlts of the third group were treated as those of the second group, but received an additional injection 2 days after their arrival at the commercial farm. Gilts were compared up to their first farrowing with regard to the appearance of oestrus, the number of the gdts which became pregnant, and the cost of supportive medication. Their litter size at farrowing, the number of piglets born alive and the litter weight have also been recorded. The results show that the number of gdts that showed oestrus and became pregnant was increased after Baypamun Iiquid treatment, particularly in the third group. The cost of supportive medication per gilt was much lower in treated groups compared to untreated animals. The treatment did not have a significant effect on the total number of piglets born, but some beneficial effect was seen in the number of piglets born alive and the average piglet weight at birth of gdts treated three times with Baypamun liquid. It was concluded that paramunization of gdts at the time of transport may improve their reproductive performance.

Immunomodulatory properties of Beta-sitosterol in pig immune responses

“…A nutraceutical is the part of the food that provides medical or health benefits, including prevention or treatment of disease [2]. Immunomodulators authorized in Europe for swine are usually administered alone or combined with vaccines by the parenteral route [3][4][5]. On the other hand, administration of products by the oral route is more suitable when the objective is to treat a large population of animals.…”

Effect of Baypamun® on Blood Leucocytes in Normal and Dexamathasone Treated Goats

“…Immunomodulation is increasingly being used in veterinary medical practice as a method of intervention to boost the immune response ( Hartmann et al . 1998 ; Roth & Flaming, 1990; Kyriakis et al . 1996 ; Ziebell et al .…”

Effects and indications regarding use of immunmodulator (Baypamun®, Bayer Vital GmbH) in horses: an overview of literature

“…In Versuchen mit Mäusen wurde durch Paramunisierung eine Wirkung auf die Leukozyten-Endothel-Interaktion nachgewiesen und eine Erhöhung der Über-lebenszeit auf den letal verlaufenden Endotoxin-Schock festgestellt (Schmitt 1995;Matzke 1999 (Kyriakis et al 1996). Die positiven Ergebnisse der Paramunisierung aus der Rinder-und Schweinereproduktion könnten auch beim Pferd erprobt werden, zumal die konventionelle lokale Behandlung von Endometriden im Sinne einer chemischen Kürettage z.…”